肺淋巴瘤或假性淋巴瘤：诊断难题

Pulmonary lymphoma or pseudolymphoma: a diagnostic dilemma.

作者信息

Chee Y C, Yap C H, Poh S C

出版信息

Ann Acad Med Singap. 1986 Jan;15(1):113-7.

Abstract

The clinical significance of pulmonary pseudolymphoma remains unresolved. We report a case which highlights the lymphoma versus pseudolymphoma dilemma. An elderly lady followed up for more than ten years with a slowly enlarging right lung mass had on biopsy, lymphoid hyperplasia consistent with a lymphoma or pseudolymphoma. Laboratory investigations revealed hyperglobulinemia due to a biclonal gammopathy with elevated serum immunoglobulin M and G fractions. Monoclonal production of immunoglobulin is today considered more indicative of a neoplasia than a hyperplasia.

摘要

肺假性淋巴瘤的临床意义仍未明确。我们报告一例病例，该病例突出了淋巴瘤与假性淋巴瘤的鉴别难题。一位老年女性，右肺肿块缓慢增大，随访十余年，活检显示淋巴样增生，符合淋巴瘤或假性淋巴瘤。实验室检查发现由于双克隆丙种球蛋白病导致高球蛋白血症，血清免疫球蛋白M和G水平升高。如今，免疫球蛋白的单克隆产生被认为比增生更能提示肿瘤形成。