Oladimeji Alaba Busola, Lamina Moriam Omolola, Ubuane Peter Odion, Adekunle Motunrayo Oluwabukola, Kehinde Omolara Adeolu, Animasahun Barakat Adeola, FidelisNjokanma Olisamedua
Department of Paediatrics, Lagos State University Teaching Hospital, Lagos, Nigeria.
Department of Paediatrics and Child Health, Lagos State University College of Medicine, Lagos, Nigeria.
Clin Exp Pediatr. 2023 May;66(5):215-222. doi: 10.3345/cep.2022.01410. Epub 2023 Apr 18.
Reference values for right ventricular dimension and systolic function in Nigerian children are scarce despite their high burden of right ventricular abnormalities. Reference values from other countries may not be suitable for use in Nigerian children because of possible racial variations in cardiac size.
To develop reference values for right ventricular dimension and systolic function in healthy Nigerian children aged 5-12 years.
This descriptive cross-sectional study conducted between July and November 2019 included 480 healthy boys and girls aged 5-12 years. The participants were randomly selected from 6 primary schools in the Ikeja Local Government area of Lagos State and their weights and heights measured. Body mass index and body surface area were calculated. Echocardiography was performed at rest in the left lateral position.
The right ventricular end-diastolic basal diameter (RVD1), right ventricular end-diastolic mid-cavity diameter (RVD2), and right ventricular end-diastolic length (RVD3) were obtained. The right ventricular end-diastolic basal diameter (RVD1), right ventricular end-diastolic mid-cavity diameter (RVD2), and right ventricular end-diastolic length (RVD3) were obtained, as well as tricuspid annular plane systolic excursion (TAPSE) and tissue Doppler-derived right ventricular systolic excursion velocity (S'). The overall mean±standard deviation (SD) values for RVD1, RVD2, RVD3, TAPSE, and S' were 32.95±4.2, 25.86±3.5, 54.57±7.5, 20.11±2.3, and 18.24±2.2, respectively. Age- and sex-specific mean and SD values of the same cardiac indices were determined. Z score charts and the mean± 2SD right ventricular dimensions and systolic function were generated. All right ventricular dimensions were positively correlated with weight, height, body surface area, and body mass index. Only height correlated consistently with TAPSE and S'.
The observed mean right ventricular dimension indices differed from those derived elsewhere, suggesting that values from other countries may be inappropriate for Nigerian children. These reference values are applicable in daily clinical practice.
尽管尼日利亚儿童右心室异常负担较重，但该国儿童右心室尺寸和收缩功能的参考值却很匮乏。由于心脏大小可能存在种族差异，其他国家的参考值可能不适用于尼日利亚儿童。
制定5至12岁健康尼日利亚儿童右心室尺寸和收缩功能的参考值。
这项描述性横断面研究于2019年7月至11月进行，纳入了480名5至12岁的健康男孩和女孩。参与者从拉各斯州伊凯贾地方政府辖区的6所小学中随机选取，并测量了他们的体重和身高。计算了体重指数和体表面积。在左侧卧位静息状态下进行超声心动图检查。
获得了右心室舒张末期基底直径（RVD1）、右心室舒张末期中间腔直径（RVD2）和右心室舒张末期长度（RVD3）。还获得了三尖瓣环平面收缩期位移（TAPSE）和组织多普勒衍生的右心室收缩期位移速度（S'）。RVD1、RVD2、RVD3、TAPSE和S'的总体平均值±标准差（SD）分别为32.95±4.2、25.86±3.5、54.57±7.5、20.11±2.3和18.24±2.2。确定了相同心脏指标的年龄和性别特异性平均值及标准差。生成了Z评分图以及平均值±2SD的右心室尺寸和收缩功能。所有右心室尺寸均与体重、身高、体表面积和体重指数呈正相关。只有身高与TAPSE和S'始终相关。
观察到的右心室尺寸指数均值与其他地方得出的不同，这表明其他国家的值可能不适用于尼日利亚儿童。这些参考值适用于日常临床实践。
