Thibault P, Dory J, Cotard J P, Moraillon J Y, Vallancien G, André-Bougaran J
Ann Urol (Paris). 1986;20(1):20-5.
A lithotriptor delivering ultrashort shockwaves and designed for use under ultrasonographic guidance has recently been developed. Immersion in water is unnecessary. The device was experimented in renal lithiasis in dogs. Twenty-two animals were treated. In seven, who served as controls, the safety of shots delivered in particular to the lungs, liver, bones and kidneys was demonstrated. Furthermore, no cardiac rhythm disorders were recorded. A human stone was implanted in 15 animals. The stone was successfully broken up in 12. Gross and microscopic examinations done 2 to 30 days after the treatment indicate that the shots initially produce lesions similar to a limited contusion. Healing of the contusion, already underway on the 8th day, is complete by the 4th week. Elimination of the fragments is gradual. The quality of fragmentation can be evaluated during the treatment session using mode A ultrasonography. These experimental data are evidence of the effectiveness of this second generation lithotriptor.
最近研发出了一种用于超声引导下、能产生超短冲击波的碎石机，无需浸泡在水中。该设备在犬肾结石治疗中进行了实验，共治疗了22只动物。其中7只作为对照，证明了向肺部、肝脏、骨骼和肾脏发射冲击波的安全性，此外，未记录到心律失常。在15只动物体内植入了人类结石，其中12只结石成功破碎。治疗后2至30天进行的大体和显微镜检查表明，冲击波最初产生的损伤类似于局限性挫伤。挫伤的愈合在第8天就已开始，第4周时完全愈合。碎片的清除是渐进的。在治疗过程中可使用A模式超声评估碎石质量。这些实验数据证明了这种第二代碎石机的有效性。
