人类肌肉萎缩症中完整红细胞的磷酸化作用
Phosphorylation of intact erythrocytes in human muscular dystrophy.
作者信息
Johnson R M, Nigro M
出版信息
Ann Neurol. 1986 Apr;19(4):397-9. doi: 10.1002/ana.410190418.
PMID:3707093
Abstract
The uptake of exogenous 32Pi into the membrane proteins of intact erythrocytes was measured in 8 patients with Duchenne muscular dystrophy. No abnormalities were noted after autoradiographic analysis. This contrasts with earlier results obtained when isolated membranes were phosphorylated with gamma-[32P]ATP, and suggests a possible reinterpretation of those experiments.
摘要
在8例杜氏肌营养不良患者中测量了外源性32P i进入完整红细胞膜蛋白的情况。放射自显影分析后未发现异常。这与早期用γ-[32P]ATP对分离的膜进行磷酸化时获得的结果形成对比，并提示对那些实验可能需要重新解释。
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