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退伍军人事务部高血压的患病率和治疗情况,评估更新后的临床指南的影响。

The prevalence and treatment of hypertension in Veterans Health Administration, assessing the impact of the updated clinical guidelines.

机构信息

Center for Access & Delivery Research and Evaluation, Iowa City VAMC.

The University of Iowa Roy J. and Lucille A Carver, College of Medicine.

出版信息

J Hypertens. 2023 Jun 1;41(6):995-1002. doi: 10.1097/HJH.0000000000003424. Epub 2023 Apr 17.

Abstract

OBJECTIVE

Hypertension is the most common risk factor for cardiovascular disease (CVD). Several guidelines have lowered diagnostic blood pressure (BP) thresholds and treatment targets for hypertension. We evaluated the impact of the more stringent guidelines among Veterans, a population at high risk of CVD.

METHODS

We conducted a retrospective analysis of Veterans with at least two office BP measurements between January 2016 and December 2017. Prevalent hypertension was defined as diagnostic codes related to hypertension, prescribed antihypertensive drugs, or office BP values according to the BP cutoffs at least 140/90 mmHg (Joint National Committee 7 [JNC 7]), at least 130/80 mmHg [American College of Cardiology/American Heart Association (ACC/AHA)], or the 2020 Veterans Health Administration (VHA) guideline (BP ≥130/90 mmHg). Uncontrolled BP was defined per the VHA guideline as mean SBP ≥130 mmHg or DBP ≥90 mmHg.

RESULTS

The prevalence of hypertension increased from 71% for BP at least 140/90 to 81% for BP at least 130/90 mmHg and further to 87% for BP at least 130/80 mmHg. Among Veterans with known hypertension ( n  = 2 768 826), a majority [ n  = 1 818 951 (66%)] were considered to have uncontrolled BP per the VHA guideline. Lowering the treatment targets for SBP and DBP significantly increased the number of Veterans who would require initiation of or intensification of pharmacotherapy. The majority of Veterans with uncontrolled BP and at least one CVD risk factor remained uncontrolled after 5 years of follow-up.

CONCLUSION

Lowering the BP diagnostic and treatment cutoffs increases the burden on healthcare systems significantly. Targeted interventions are needed to achieve the BP treatment goals.

摘要

目的

高血压是心血管疾病(CVD)最常见的危险因素。多项指南已经降低了高血压的诊断血压(BP)阈值和治疗目标。我们评估了这些更严格的指南在退伍军人中的影响,退伍军人是 CVD 高危人群。

方法

我们对 2016 年 1 月至 2017 年 12 月期间至少有两次门诊 BP 测量的退伍军人进行了回顾性分析。高血压的患病率定义为根据 BP 切点存在与高血压相关的诊断代码、开有降压药物或门诊 BP 值,至少 140/90mmHg(联合国家委员会 7 [JNC 7])、至少 130/80mmHg [美国心脏病学会/美国心脏协会(ACC/AHA)],或 2020 年退伍军人健康管理局(VHA)指南(BP≥130/90mmHg)。根据 VHA 指南,BP 未得到控制定义为平均 SBP≥130mmHg 或 DBP≥90mmHg。

结果

高血压的患病率从至少 140/90mmHg 的 71%增加到至少 130/90mmHg 的 81%,进一步增加到至少 130/80mmHg 的 87%。在已知患有高血压的退伍军人中(n=2768826),根据 VHA 指南,大多数(n=1818951 [66%])被认为 BP 未得到控制。降低 SBP 和 DBP 的治疗目标显著增加了需要开始或加强药物治疗的退伍军人数量。大多数 BP 未得到控制且至少有一个 CVD 风险因素的退伍军人在 5 年的随访后仍未得到控制。

结论

降低 BP 诊断和治疗阈值会显著增加医疗保健系统的负担。需要采取有针对性的干预措施来实现 BP 治疗目标。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c792/10158602/dc7e539085b4/jhype-41-0995-g001.jpg

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