Centre for Health Performance and Wellbeing, Anglia Ruskin University, Cambridge, UK.
Division of Preventive Medicine and Public Health, Department of Public Health Sciences, School of Medicine, University of Murcia, Murcia, Spain.
J Gerontol A Biol Sci Med Sci. 2024 Jan 1;79(1). doi: 10.1093/gerona/glad104.
There is a scarcity of studies examining the longitudinal relationship between dynapenic abdominal obesity (DAO; ie, impairment in muscle strength and high waist circumference) and future fall risk. Therefore, we aimed to investigate the prospective association between DAO at baseline and falls occurring during 2 years of follow-up in a nationally representative sample of middle-aged and older individuals from Ireland.
Data from 2 consecutive waves of the Irish Longitudinal Study on Ageing survey were analyzed. Dynapenia was defined as handgrip strength of <26 kg for men and <16 kg for women. Abdominal obesity was defined as a waist circumference of >88 cm for women and >102 cm for men. DAO was assessed at Wave 1 (2009-2011) and was defined as having both dynapenia and abdominal obesity. Falls occurring between Wave 1 and Wave 2 (2012-2013) were self-reported. Multivariable logistic regression analysis was conducted.
Data on 5 275 individuals aged ≥50 years were analyzed (mean [standard deviation {SD}] age 63.2 [8.9] years; 48.8% males). After adjustment for potential confounders, compared to no dynapenia and no abdominal obesity at baseline, DAO was significantly associated with 1.47 (95% confidence interval [CI]: 1.14-1.89) times higher odds for falls at 2-year follow-up. Dynapenia alone (odds ratio [OR] = 1.08; 95% CI: 0.84-1.40) and abdominal obesity alone (OR = 1.09; 95% CI: 0.91-1.29) were not significantly associated with falls at follow-up.
DAO increased the risk for falls among middle-aged and older adults in Ireland. Interventions to prevent or reverse DAO may be beneficial for fall reduction.
目前缺乏研究探讨 dynapenic 腹部肥胖(DAO;即肌肉力量受损和高腰围)与未来跌倒风险之间的纵向关系。因此,我们旨在调查爱尔兰具有代表性的中年和老年人样本中,基线时 DAO 与随访 2 年内发生跌倒之间的前瞻性关联。
对爱尔兰老龄化纵向研究调查的两个连续波次的数据进行了分析。握力<26kg 为男性,<16kg 为女性,定义为 dynapenia。腰围>88cm 为女性,>102cm 为男性,定义为腹部肥胖。DAO 在第 1 波(2009-2011 年)进行评估,定义为同时存在 dynapenia 和腹部肥胖。第 1 波和第 2 波(2012-2013 年)之间报告的跌倒事件。采用多变量逻辑回归分析。
分析了 5275 名年龄≥50 岁的个体数据(平均[标准差]年龄 63.2[8.9]岁;48.8%为男性)。在调整了潜在混杂因素后,与基线时无 dynapenia 且无腹部肥胖相比,DAO 与 2 年随访时跌倒的风险比为 1.47(95%置信区间[CI]:1.14-1.89)显著相关。仅 dynapenia(比值比[OR] = 1.08;95%CI:0.84-1.40)和仅腹部肥胖(OR = 1.09;95%CI:0.91-1.29)与随访时的跌倒无显著相关性。
DAO 增加了爱尔兰中年和老年人跌倒的风险。预防或逆转 DAO 的干预措施可能有益于减少跌倒。