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双侧 EBV 感染相关性脑回样血管炎患儿的多模态影像学表现

Multimodal Imaging of a Case of Bilateral Frosted Branch Angiitis in a 5-Year-Old Boy Secondary to Epstein Barr Virus (EBV) Infection.

机构信息

Department of Uvea, Medical Research Foundation, Sankara Nethralaya, Chennai, India.

出版信息

Ocul Immunol Inflamm. 2024 Aug;32(6):1117-1120. doi: 10.1080/09273948.2023.2194412. Epub 2023 Apr 18.

DOI:10.1080/09273948.2023.2194412
PMID:37071816
Abstract

PURPOSE

To describe a rare case of bilateral frosted branch angiitis with macular exudates in a 5-year-old boy presumed to be secondary to an Epstein-Barr virus (EBV) infection.

OBSERVATIONS

A 5-year-old boy presented with acute onset blurring of vision in both eyes, the best corrected visual acuity was 3/60 in both eyes. The anterior segment was unremarkable, fundus showed the presence of perivascular sheathing involving the macular vessels, exudates, and subretinal fluid at the fovea (OU). Serology was positive for EBV. Swept-source optical coherence tomography angiography showed areas of flow void in the superficial and deep capillary plexus that disappeared with reduction of inflammation following treatment with intravenous, oral and topical steroids, and oral valacyclovir.

CONCLUSIONS

Frosted branch angiitis can present following an EBV infection.

摘要

目的

描述一例 5 岁男孩双侧血管白鞘伴黄斑渗出,推测为 EBV 感染所致。

观察

一名 5 岁男孩因双眼视力突然模糊就诊,最佳矫正视力双眼均为 3/60。眼前节无明显异常,眼底可见黄斑区血管周围鞘膜、渗出物和视网膜下积液(双眼)。血清学 EBV 阳性。扫频源光学相干断层扫描血管造影显示浅层和深层毛细血管丛存在血流缺失区,经静脉、口服和局部皮质类固醇以及口服伐昔洛韦治疗炎症减轻后消失。

结论

血管白鞘炎可继发于 EBV 感染。

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