Department of Ophthalmology, Armed Forces Medical College, Pune, India.
Ocul Immunol Inflamm. 2024 Aug;32(6):1121-1123. doi: 10.1080/09273948.2023.2195933. Epub 2023 Apr 18.
To report a case of ocular toxoplasmosis as a rare complication of intravitreal dexamethasone implant in a case of diabetic macular edema.
A 56 years old male, a known case of Proliferative Diabetic Retinopathy, received intravitreal dexamethasone implant for diabetic macular edema in left eye. He developed toxoplasma retinochoroiditis involving the macula with further diminution of vision in his left eye 3 weeks after the injection. His serum titres were positive for Toxoplasma IgG (161 IU/ml). He was treated with oral Sulfamethoxazole 800 mg + Trimethoprim 160 mg 12 hourly for 4 weeks.
The visual acuity in left eye improved with resolution of retinochoroiditis after the course of antibiotic therapy.
It is imperative to follow-up closely after intravitreal steroid implantation, to look for the possible rare complication of infectious retinitis/retinochoroiditis, as timely antimicrobial treatment can lead to a good visual outcome.
报告一例眼弓形体病，这是玻璃体内注射地塞米松植入物治疗糖尿病性黄斑水肿的罕见并发症。
一名 56 岁男性，患有增殖性糖尿病性视网膜病变，左眼接受玻璃体内地塞米松植入物治疗糖尿病性黄斑水肿。在注射后 3 周，他出现了累及黄斑的弓形体性视网膜脉络膜炎，左眼视力进一步下降。他的血清滴度对弓形虫 IgG 呈阳性（161 IU/ml）。他接受了口服磺胺甲恶唑 800 mg+甲氧苄啶 160 mg，每 12 小时 1 次，共 4 周的治疗。
在抗生素治疗后，左眼的视力得到了改善，视网膜脉络膜炎也得到了缓解。
在玻璃体内类固醇植入物后密切随访至关重要，以寻找可能的罕见感染性视网膜炎/脉络膜炎并发症，因为及时的抗菌治疗可以带来良好的视觉结果。
