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成人法洛四联症的临床特征与外科治疗:200例修复手术的结果

The clinical profile and surgical treatment of tetralogy of Fallot in the adult: results of repair in 200 patients.

作者信息

John S, Kejriwal N K, Ravikumar E, Bashi V V, Mohanty B B, Sukumar I P

出版信息

Ann Thorac Surg. 1986 May;41(5):502-6. doi: 10.1016/s0003-4975(10)63028-7.

Abstract

This report describes our 17-year experience with intracardiac repair in 200 patients older than 14 years with tetralogy of Fallot. Congestive failure, hemoptysis, and cerebral abscess were present in 15, 10, and 3% of patients, respectively. Prior palliative shunts had been performed in 24.5% only. Polycythemia with a hematocrit greater than 60% was noted in 100 patients but was not considered an incremental risk factor (p greater than 0.05). A transannular gusset was utilized in 74% of patients in the last 5 years of the study. Hospital mortality was 1.3% in the last 5 years. Ninety-seven percent of survivors at follow-up are asymptomatic and leading an active life. Recatheterization data from 86 patients revealed excellent or good results in 88%. The incidence of residual ventricular defect was 1% overall, with a zero incidence in the last 12 years. On the basis of this review, we consider that easier and hemodynamically satisfactory repair has been achieved in the adolescent and older patient compared with the child. The ultimate longevity, however, must await the results of long-term functional and serial hemodynamic evaluation.

摘要

本报告描述了我们对200例14岁以上法洛四联症患者进行心内修复的17年经验。充血性心力衰竭、咯血和脑脓肿的发生率分别为15%、10%和3%。仅24.5%的患者曾接受过姑息性分流术。100例患者出现血细胞比容大于60%的红细胞增多症,但未被视为增加风险因素(P>0.05)。在研究的最后5年中,74%的患者使用了跨环补片。过去5年的医院死亡率为1.3%。随访中97%的幸存者无症状,过着积极的生活。86例患者的再次导管检查数据显示,88%的结果为优秀或良好。残余室间隔缺损的总体发生率为1%,最近12年的发生率为零。基于此综述,我们认为与儿童相比,青少年及成年患者的修复更容易且血流动力学效果更佳。然而,最终的寿命情况仍需等待长期功能和系列血流动力学评估的结果。

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