Oral and Dental Disease Research Center, Oral and Maxillofacial Radiology Department, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.
School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.
Cleft Palate Craniofac J. 2024 Jul;61(7):1172-1178. doi: 10.1177/10556656231165189. Epub 2023 Apr 18.
Superior Semicircular Canal Dehiscence (SSCD) is a recently-defined developmental defect may be associated with several craniofacial anomalies such as Cleft Lip/Palate (CLP). The present study aimed to compare subjects with unilateral and bilateral CLP and normal controls in terms of Superior Semicircular Canal (SSC) bone thickness and pattern. A total of 238 Cone Beam Computed Tomography (CBCT) images were collected from 52 unilateral Cleft Lip and Palate (UCLP) subjects (104 temporal bones) and 38 Bilateral Cleft Lip and Palate (BCLP) (76 temporal bones) subjects and 148 healthy controls (296 temporal bones). The SSC bone thickness was measured twice and validated by a maxillofacial radiologist. The samples were then classified into five categories based on bone thickness: papyraceous or thin, normal, thick, pneumatized, and dehiscence. After all, the UCLP, BCLP, and normal control groups were compared concerning the SSC pattern and thickness. The results revealed no significant difference among the three groups regarding the SSC pattern and thickness based on gender. The SSC patterns ( value = .001) and SSC thickness (0.01) were strongly correlated to the cleft type. The thinnest bone thickness and the highest incidence of SSCD were observed among the subjects with BCLP. The results showed a significant association between the SSC patterns and SSC thickness and the study groups.
上半规管裂（SSCD）是一种新定义的发育缺陷，可能与多种颅面畸形有关，如唇裂/腭裂（CLP）。本研究旨在比较单侧和双侧 CLP 患者与正常对照组在上半规管（SSC）骨厚度和形态方面的差异。共收集了 52 例单侧唇裂和腭裂（UCLP）患者（104 侧颞骨）、38 例双侧唇裂和腭裂（BCLP）患者（76 侧颞骨）和 148 例健康对照组（296 侧颞骨）的 238 例锥形束 CT（CBCT）图像。两次测量 SSC 骨厚度，并由颌面放射科医生进行验证。然后根据骨厚度将样本分为五类：纸样或薄、正常、厚、充气和裂。最后，比较 UCLP、BCLP 和正常对照组的 SSC 形态和厚度。结果显示，基于性别，三组之间 SSC 形态和厚度无显著差异。SSC 形态（P 值 = .001）和 SSC 厚度（0.01）与裂隙类型强烈相关。在 BCLP 患者中，骨厚度最薄，SSCD 发生率最高。结果表明，SSC 形态和 SSC 厚度与研究组之间存在显著相关性。
