Sureshkumar Mathavi, Rajamani Shanmugasundaram, Ravindran Vijayaragavan, ArvindhKrishnan E
Department of Microbiology, Vinayaka Mission's Kirupananda Variyar Medical College, Vinayaka Missions Research Foundation (Deemed to be University), Salem, Tamil Nadu, India.
Department of General Medicine, Vinayaka Mission's Kirupananda Variyar Medical College, Vinayaka Missions Research Foundation (Deemed to be University), Salem, Tamil Nadu, India.
Indian J Pathol Microbiol. 2023 Apr-Jun;66(2):350-351. doi: 10.4103/ijpm.ijpm_341_21.
TB arthritis is a very rare extrapulmonary presentation in an immunocompetent host. It is usually the result of direct hematogenous spread from the primary focus. Our patient presented with pain and swelling of the right knee for 6 months. The blood investigations and CT chest revealed findings consistent with active tuberculosis. Synovial fluid was positive for acid-fast bacilli (AFB) which is a very rare finding. Cartridge-based nucleic acid amplification test (CBNAAT) revealed Mycobacterium tuberculosis and sensitivity to rifampicin. Establishing the diagnosis of Mycobacterium tuberculosis beyond doubt is very important, and early initiation of antitubercular treatment (ATT) is important as delay in treatment may lead to irreversible damage to the joint and restriction of joint mobility.
结核性关节炎在免疫功能正常的宿主中是一种非常罕见的肺外表现。它通常是原发灶直接血行播散的结果。我们的患者出现右膝疼痛和肿胀6个月。血液检查和胸部CT显示的结果与活动性肺结核相符。滑液中抗酸杆菌（AFB）呈阳性，这是一个非常罕见的发现。基于 cartridge 的核酸扩增试验（CBNAAT）显示为结核分枝杆菌且对利福平敏感。毫无疑问地确立结核分枝杆菌的诊断非常重要，尽早开始抗结核治疗（ATT）也很重要，因为治疗延迟可能导致关节不可逆转的损伤和关节活动受限。
