Neering I R, Fryer M W
Biochim Biophys Acta. 1986 Jun 3;882(1):39-43. doi: 10.1016/0304-4165(86)90052-8.
The effect of alcohols from ethanol to octanol on aequorin luminescence was biphasic; enhancement of both peak light and total photon yield at low concentrations, and inhibition of these parameters at high concentrations. The potency of alcohols to exert these effects was in the same order as the oil/water partition coefficients of the alcohols. It is argued that neither of these effects is related to calcium binding by aequorin, since alcohols enhanced calcium-independent luminescence, and the inhibition of responses is not associated with a reduction in the rate of aequorin 'consumption' on binding of calcium.
从乙醇到辛醇的醇类对水母发光蛋白发光的影响是双相的；低浓度时峰值光和总光子产量均增强，高浓度时则抑制这些参数。醇类产生这些效应的效力与醇类的油/水分配系数顺序相同。有人认为，这些效应均与水母发光蛋白的钙结合无关，因为醇类增强了不依赖钙的发光，且反应的抑制与钙结合时水母发光蛋白“消耗”速率的降低无关。
