International Institute for Population Sciences, Mumbai, Maharashtra, India
BMJ Open. 2023 Apr 20;13(4):e070830. doi: 10.1136/bmjopen-2022-070830.
To examine the association between hysterectomy and hypertension among middle-aged and older women in India, as well as to determine if the association differs across different age groups.
A cross-sectional exploratory study.
Nationally representative population-based data of the Longitudinal Ageing Study in India (2017-2018) were used in this study. The sample included 32 460 women aged 45 years and above.
Self-reported hypertension was the outcome variable. The variable was a binary variable, with 1 representing hypertensive and 0 representing not hypertensive.
Entropy balance method, along with logistic regression analysis, was used to meet the objectives.
31.3% of the women with hysterectomy and 42.5% of the women without hysterectomy were hypertensive. A perfect covariate balance was achieved between the treatment and control groups using the entropy balance method. Women with hysterectomy had 36% (OR 1.36; 95% CI 1.26 to 1.48) higher odds of hypertension than women without hysterectomy. The OR was 1.23 (95% CI 1.03 to 1.47) for the age group 45-49, whereas, for the age group 80+, it was 1.87 (95% CI 1.18 to 2.97), showing that the magnitude of the association between hysterectomy and hypertension varied with age.
The findings of this study suggest that hysterectomy and hypertension have a significant association in middle-aged as well as older women in India.
探讨印度中年及以上女性子宫切除术与高血压之间的关联,并确定这种关联在不同年龄组之间是否存在差异。
这是一项横断面探索性研究。
本研究使用了印度纵向老龄化研究(2017-2018 年)的全国代表性人口基础数据。样本包括 32460 名年龄在 45 岁及以上的女性。
自我报告的高血压是结局变量。该变量为二分类变量,1 代表高血压,0 代表非高血压。
采用熵平衡法和逻辑回归分析来达到研究目的。
31.3%的子宫切除术患者和 42.5%的未行子宫切除术患者患有高血压。通过熵平衡法,在治疗组和对照组之间实现了完美的协变量平衡。与未行子宫切除术的女性相比,行子宫切除术的女性高血压的可能性高 36%(OR 1.36;95%CI 1.26 至 1.48)。45-49 岁年龄组的 OR 为 1.23(95%CI 1.03 至 1.47),而 80 岁及以上年龄组的 OR 为 1.87(95%CI 1.18 至 2.97),表明子宫切除术与高血压之间的关联程度随年龄而变化。
本研究结果表明,子宫切除术与印度中年及以上女性的高血压之间存在显著关联。