口腔周围神经鞘瘤的最新进展。
An update on oral peripheral nerve sheath tumors.
作者信息
Santana N, Hemapriya G, Shakthivel R Malavika, Karunakaran Vishnupriya C
机构信息
Department of Oral Medicine and Radiology, Ragas Dental College and Hospital, Chennai, Tamil Nadu, India.
出版信息
J Oral Maxillofac Pathol. 2022 Oct-Dec;26(4):541-552. doi: 10.4103/jomfp.jomfp_441_21. Epub 2022 Dec 22.
Abstract
Peripheral nerve sheath tumors (PNSTs) are defined as type of sarcomas that develops in cells which forms a protective sheath (covering) around the peripheral nerve, i.e., the cells of myelin sheath. Nerve tumors are of neuroectodermal in origin as it was composed of small rounded ectodermal cells that affect exclusively soft tissues. PNSTs are most common neoplasm with classic clinicopathological features, but they are diagnostically challenging. They consist of wide spectrum of tumors ranging from benign tumors to malignant nerve sheath tumors and its prevalent in oral tissues. Diagnosis of PNSTs are quite hectic but made possible by histopathology and immunohistological markers.
摘要
周围神经鞘瘤（PNSTs）被定义为一种肉瘤，它发生在围绕周围神经形成保护性鞘（覆盖物）的细胞中，即髓鞘细胞。神经肿瘤起源于神经外胚层，因为它由专门影响软组织的小圆形外胚层细胞组成。PNSTs是具有典型临床病理特征的最常见肿瘤，但在诊断上具有挑战性。它们包括从良性肿瘤到恶性神经鞘瘤的广泛肿瘤类型，并且在口腔组织中很常见。PNSTs的诊断相当复杂，但通过组织病理学和免疫组织学标志物可以实现诊断。
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