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在原型模拟器中暴露于实验加载条件下的氧化锆和聚醚醚酮生物材料的生物力学行为比较研究。

Comparative study on biomechanical behavior of zirconia and polyetheretherketone biomaterials exposed to experimental loading conditions in a prototypal simulator.

机构信息

Tecnologica Research Institute - Marrelli Health, 88900 Crotone, Italy.

Department of Neurosciences, Reproductive and Odontostomatological Sciences, Postgraduate School of Oral Surgery, University "Federico II" of Naples, via S. Pansini 5, 80131 Naples, Italy.

出版信息

Int J Med Sci. 2023 Apr 2;20(5):639-651. doi: 10.7150/ijms.82297. eCollection 2023.

Abstract

Zirconia and polyetheretherketone (PEEK) are two biomaterials widely investigated as substitute for metals in oral prosthetic rehabilitation. To achieve a proper biomechanical behavior, the prosthetic biomaterials must ensure a good resistance to loads, as this is a crucial characteristic enabling their use in dental applications. The aim of this study was to investigate differences in the fracture resistance of different biomaterials in an experimental environment: fixed partial dentures (FPDs) screwed in a prototype of biomimetic mandible. 10 Samples of FPDs were allocated in 2 groups (A and B): Group A (n=5) involved FPDs in zirconia-ceramic, and Group B (n=5) involved FPDs in PEEK-composite. The samples were loaded by means of a three-point bending mechanical test, and the load to fracture has been evaluated generating a point-by-point graphics (speed/load and time/deformation). The samples were further analyzed by micro-computed tomography (micro-CT) and described under experimental loading conditions. Zirconia-ceramic FDPs were the samples reporting the worst results, showing a lower value of vertical displacement with respect to PEEK-based samples. The micro-CT results have further confirmed the preliminary results previously described. This study aims to give analytic data on the reliability of PEEK as a reliable and strong biomaterial for prosthetic treatments.

摘要

氧化锆和聚醚醚酮(PEEK)是两种广泛研究的生物材料,作为口腔修复体替代金属的材料。为了实现适当的生物力学性能,修复体生物材料必须确保对负荷有良好的抵抗力,因为这是使其在牙科应用中使用的关键特征。本研究的目的是在实验环境中研究不同生物材料的断裂阻力差异:旋入仿生下颌原型中的固定局部义齿(FPD)。将 10 个 FPD 样本分配到 2 个组(A 和 B)中:组 A(n=5)包括氧化锆陶瓷 FPD,组 B(n=5)包括 PEEK 复合材料 FPD。通过三点弯曲机械试验对样本进行加载,并通过逐点图形(速度/负载和时间/变形)评估断裂负载。对样本进行进一步的微计算机断层扫描(micro-CT)分析,并在实验加载条件下进行描述。氧化锆陶瓷 FDP 是报告结果最差的样本,与基于 PEEK 的样本相比,其垂直位移值较低。微 CT 结果进一步证实了之前描述的初步结果。本研究旨在提供关于 PEEK 作为一种可靠且坚固的修复体治疗用生物材料的可靠性的分析数据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db57/10110469/d6e7ef560f57/ijmsv20p0639g001.jpg

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