Leszczyński Piotr, Pietras Tadeusz, Mokros Łukasz
Department of Clinical Pharmacology, Medical University of Lodz, Poland.
Postep Psychiatr Neurol. 2021 Sep;30(3):190-196. doi: 10.5114/ppn.2021.110679. Epub 2021 Nov 26.
The goal of this study is a review of the literature on the role of alexithymia among stroke patients, especially assessing its impact on the process of convalescence, psychiatric comorbidity and clinical outcomes.
Organic alexithymia is a common post-stroke complication, which interferes with many aspects of health among stroke survivors, with interleukin-18 having an important role in the appearance and depth of alexithymia. Post-stroke patients suffering from alexithymia are more prone to depression, manifestations of which may differ from the symptoms of this shown by the non-alexithymic post-stroke population. Alexithymia is also the cause of more severe symptoms of stroke itself, as well as more severe symptoms of post-stroke post-traumatic stress disorder. It is often associated with right-hemisphere lesions, but there are findings which show that left brain insult may also be the cause; the explanation is that information transfer from right to left hemisphere causes disturbances in emotional awareness.
Alexithymia plays an important role in the health of post-stroke patients. Assessment of the trait should be considered in their population, since it plays an important role in terms of predicting psychiatric comorbidity and severity of stroke complications, which transfers to treatment choice. Further research is required to examine other post-stroke psychiatric comorbidities associated with alexithymia and to closely determine the response of rehabilitation, including pharmacological treatment and psychological therapy.
本研究的目的是回顾关于述情障碍在中风患者中的作用的文献,特别是评估其对康复过程、精神共病和临床结局的影响。
器质性述情障碍是中风后常见的并发症,它会干扰中风幸存者健康的多个方面,白细胞介素-18在述情障碍的出现和严重程度方面起着重要作用。患有述情障碍的中风后患者更容易出现抑郁,其表现可能与非述情障碍中风后人群的抑郁症状不同。述情障碍也是中风本身更严重症状以及中风后创伤后应激障碍更严重症状的原因。它常与右半球病变有关,但也有研究结果表明左脑损伤也可能是原因;其解释是从右半球到左半球的信息传递会导致情绪意识紊乱。
述情障碍在中风后患者的健康中起着重要作用。在这一人群中应考虑对该特质进行评估,因为它在预测精神共病和中风并发症严重程度方面起着重要作用,而这又会影响治疗选择。需要进一步研究以检查与述情障碍相关的其他中风后精神共病,并密切确定康复反应,包括药物治疗和心理治疗。