Pinna Federica, Manchia Mirko, Paribello Pasquale, Carpiniello Bernardo
Section of Psychiatry, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy.
Unit of Clinical Psychiatry, University Hospital of Cagliari, Cagliari, Italy.
Front Psychiatry. 2020 Apr 16;11:311. doi: 10.3389/fpsyt.2020.00311. eCollection 2020.
Treatment of psychiatric disorders relies heavily on a trial and error approach, often prolonging the time required to obtain symptomatic improvements. The identification of reliable predictors of treatment response is instrumental to enact an individualized approach. Alexithymia represents a personality trait reflecting an intrinsic difficulty in recognizing the emotional components of subjective experiences. Thus, its modulating role on treatment outcome has gathered substantial attention during the past years. In the present paper, we aimed at exploring the available evidence for Alexithymia role in influencing the treatment outcome on a wide range of psychiatric conditions by means of a systematic review.
We performed a systematic review in Medline and Scopus, augmented by tracking the reference list of the pertinent articles.
To be included in this review, research studies had to assess alexithymia impact on a treatment intervention delivered to manage a primary psychiatric disorder.
After removing duplicates, titles were screened first, then abstracts, and last full texts were read, eventually leading to the inclusion or exclusion of the papers according to the criteria established before the online search. Then results of the search were downloaded in.xml format and uploaded in Rayyan, a free web software, that helps expedite the initial screening of abstracts and titles using a process of semi-automation while incorporating a high level of usability. After uploading, screening of the literature was performed in blind by two investigators. Disagreement between reviewers was resolved by joint discussion with a third senior investigator. The quality of evidence was assessed using the Newcastle Ottawa Scale. Thereafter, the data considered relevant was extracted and synthetized in this paper.
Our search yielded a total of 30 articles dealing with a wide range of psychiatric conditions and exploring both pharmacological and psychotherapeutic interventions. Several lines of evidence suggest a complex role for alexithymia in influencing the psychiatric treatment outcome, further underscoring the need for additional research in this area to better address the existing knowledge gaps.
精神疾病的治疗严重依赖反复试验的方法，这常常延长了获得症状改善所需的时间。确定可靠的治疗反应预测指标有助于制定个性化的治疗方法。述情障碍是一种人格特质，反映了个体在识别主观体验中的情感成分方面存在内在困难。因此，它在治疗结果中的调节作用在过去几年中受到了广泛关注。在本文中，我们旨在通过系统综述来探索有关述情障碍在影响多种精神疾病治疗结果方面作用的现有证据。
我们在Medline和Scopus数据库中进行了系统综述，并通过追踪相关文章的参考文献列表进行补充。
要纳入本综述，研究必须评估述情障碍对用于治疗原发性精神疾病的治疗干预措施的影响。
去除重复项后，首先筛选标题，然后筛选摘要，最后阅读全文，最终根据在线搜索前确定的标准决定文章的纳入或排除。然后将搜索结果以.xml格式下载并上传到Rayyan（一款免费的网络软件），该软件有助于通过半自动化过程加快对摘要和标题的初步筛选，同时具有高度的可用性。上传后，由两名研究人员对文献进行盲法筛选。评审人员之间的分歧通过与第三位资深研究人员共同讨论来解决。使用纽卡斯尔渥太华量表评估证据质量。此后，提取并综合了本文中认为相关的数据。
我们的搜索共产生了30篇文章，涉及多种精神疾病，并探讨了药物治疗和心理治疗干预措施。几条证据线索表明述情障碍在影响精神疾病治疗结果方面具有复杂的作用，进一步强调了该领域需要更多研究以更好地填补现有知识空白。
