甲氨蝶呤相关性淋巴组织增生性疾病的肝脏超级扫描。

Hepatic Superscan in Methotrexate-Associated Lymphoproliferative Disorder.

机构信息

From the Nuclear Medicine Unit, Department of Radiology, Queen Mary Hospital, Hong Kong.

出版信息

Clin Nucl Med. 2023 Jun 1;48(6):534-535. doi: 10.1097/RLU.0000000000004647. Epub 2023 Apr 24.

Abstract

A 60-year-old man on methotrexate for treatment of adult-onset Still disease presented with acute onset of fever, pancytopenia, and deranged liver function. Besides FDG-avid lesions in spleen and skeleton, his 18 F-FDG PET/CT study showed diffuse and intense uptake in the liver with significantly suppressed heart and brain activity (reminiscent of a hepatic superscan). Subsequent biopsy confirmed the diagnosis of methotrexate-associated lymphoproliferative disorder.

摘要

一位 60 岁男性因成人斯蒂尔病接受甲氨蝶呤治疗，突发发热、全血细胞减少和肝功能异常。除了脾脏和骨骼的 FDG 摄取病灶外，他的 18 F-FDG PET/CT 研究显示肝脏弥漫性和强烈摄取，心脏和大脑活性明显受抑制（类似于肝超扫描）。随后的活检证实了甲氨蝶呤相关性淋巴组织增生性疾病的诊断。