Department of eyeSmart EMR & AEye, L V Prasad Eye Institute, Hyderabad, India.
Indian Health Outcomes, Public Health and Economics Research Centre, Hyderabad, India.
Ocul Immunol Inflamm. 2024 Jul;32(5):722-726. doi: 10.1080/09273948.2023.2199331. Epub 2023 Apr 21.
To describe the clinical profile of patients presented with keratitis (AK) to a multi-tier ophthalmology hospital network in India.
This cross-sectional hospital-based study included 1945339 new patients registering between September 2016 and May 2022. Patients with clinically confirmed diagnosis of AK in one or both eyes were included in the study. All the relevant data were documented using an electronic medical record (EMR) system.
A total of 245 (0.013%) patients were diagnosed with AK and majority were male (62.86%) with unilateral (99.59%) affliction. The most common age group was during the fourth decade of life, 65 (26.53%) patients and predominantly were adults (95.51%). The prevalence of the infection was higher in patients from a lower socioeconomic status (43.27%) from rural geography (52.24%) and in agriculture-related work (28.16%). The most common inciting factor was injury with vegetative matter (8.98%), dust (7.76%) and contact lens wear (4.49%). The majority of the eyes had blindness (20/400 to 20/1200) in 116 (47.15%) eyes with a presenting visual acuity (logMAR) of 2.14 ± 1.04. Among the surgical interventions, therapeutic keratoplasty was performed in 41 (16.67%) eyes, penetrating keratoplasty in 22 (8.94%) eyes, and evisceration in 2 (0.81%) eyes.
AK more commonly affects males presenting during the fourth decade of life from lower socio-economic status and is predominantly unilateral. A fourth of the affected eyes underwent keratoplasty and the majority had significant visual impairment at presentation.
描述在印度一家多层次眼科医院网络就诊的角膜炎(AK)患者的临床特征。
这是一项基于医院的横断面研究,纳入了 2016 年 9 月至 2022 年 5 月期间登记的 1945339 名新患者。将在一只或两只眼中经临床确诊为 AK 的患者纳入研究。所有相关数据均使用电子病历(EMR)系统记录。
共有 245 名(0.013%)患者被诊断为 AK,其中大多数为男性(62.86%),单侧受累(99.59%)。最常见的年龄组为 40 多岁,有 65 名(26.53%)患者,主要为成年人(95.51%)。感染的发生率在社会经济地位较低(43.27%)、来自农村地区(52.24%)和从事农业相关工作(28.16%)的患者中较高。最常见的诱发因素是植物性物质(8.98%)、灰尘(7.76%)和隐形眼镜佩戴(4.49%)导致的损伤。116 只眼中有 41 只(47.15%)视力丧失(20/400 至 20/1200),视力(logMAR)为 2.14±1.04。在手术干预中,41 只眼(16.67%)行治疗性角膜移植术,22 只眼(8.94%)行穿透性角膜移植术,2 只眼(0.81%)行眼内容剜除术。
AK 更常见于社会经济地位较低的男性,在第四十年发病,主要为单侧。四分之一的受累眼行角膜移植术,大多数患者就诊时视力严重受损。