Laboratoire Reproduction et Développement des Plantes, Université de Lyon, ENS de Lyon, UCB Lyon 1, CNRS, INRAe, F-69342, Lyon, France.
Laboratoire Reproduction et Développement des Plantes, Université de Lyon, ENS de Lyon, UCB Lyon 1, CNRS, INRAe, F-69342, Lyon, France.
Curr Opin Plant Biol. 2023 Jun;73:102365. doi: 10.1016/j.pbi.2023.102365. Epub 2023 Apr 19.
Plants have developed fine-tuned cellular mechanisms to respond to a variety of intracellular and extracellular signals. These responses often necessitate the rearrangement of the plant cytoskeleton to modulate cell shape and/or to guide vesicle trafficking. At the cell periphery, both actin filaments and microtubules associate with the plasma membrane that acts as an integrator of the intrinsic and extrinsic environments. At this membrane, acidic phospholipids such as phosphatidic acid, and phosphoinositides contribute to the selection of peripheral proteins and thereby regulate the organization and dynamic of the actin and microtubules. After recognition of the importance of phosphatidic acid on cytoskeleton dynamics and rearrangement, it became apparent that the other lipids might play a specific role in shaping the cytoskeleton. This review focuses on the emerging role of the phosphatidylinositol 4,5-bisphosphate for the regulation of the peripherical cytoskeleton during cellular processes such as cytokinesis, polar growth, biotic and abiotic responses.
植物已经进化出精细的细胞机制来响应各种细胞内和细胞外的信号。这些反应通常需要重新排列植物细胞骨架，以调节细胞形状和/或引导囊泡运输。在细胞边缘，肌动蛋白丝和微管都与作为内在和外在环境整合者的质膜结合。在这个膜上，酸性磷脂，如磷脂酸和磷酸肌醇，有助于外周蛋白的选择，从而调节肌动蛋白和微管的组织和动态。在认识到磷脂酸在细胞骨架动力学和重排中的重要性之后，显然其他脂质可能在塑造细胞骨架方面发挥特定作用。本综述重点介绍了磷脂酰肌醇 4,5-二磷酸在细胞过程（如胞质分裂、极性生长、生物和非生物响应）中调节外周细胞骨架的新作用。
