新型冠状病毒肺炎对非肺部危重症的影响：患病率、临床表现、治疗及预后。
Impact of COVID-19 on Nonpulmonary Critical Illness: Prevalence, Clinical Manifestations, Management, and Outcomes.
机构信息
Division of Pulmonary and Critical Care Medicine, University of Michigan, Ann Arbor, MI 48109, USA; Veterans Affairs Ann Arbor Healthcare System, Ann Arbor, MI 48105, USA.
Division of Pulmonary and Critical Care Medicine, University of Michigan, Ann Arbor, MI 48109, USA; Veterans Affairs Ann Arbor Healthcare System, Ann Arbor, MI 48105, USA; VA Center for Clinical Management Research, University of Michigan, Ann Arbor, MI 48109, USA.
出版信息
Clin Chest Med. 2023 Jun;44(2):249-262. doi: 10.1016/j.ccm.2022.11.011. Epub 2022 Nov 23.
Although respiratory manifestations are the most common driver of hospitalization, SARS-CoV-2 infection has a wide range of manifestations, including multisystem organ failure in severe cases. This review discusses the prevalence, pathophysiology, clinical manifestations, treatment, and outcomes of nonpulmonary organ dysfunction from SARS-CoV2, including renal, liver, cardiac, neurologic, and coagulation system dysfunction. At this time, management largely focuses on supportive care practices that are applicable regardless of the cause of organ injury.
尽管呼吸道症状是导致住院的最常见原因，但严重的 SARS-CoV-2 感染有广泛的表现，包括多系统器官衰竭。本文讨论了 SARS-CoV-2 引起的非肺部器官功能障碍的流行情况、发病机制、临床表现、治疗和结局，包括肾脏、肝脏、心脏、神经和凝血系统功能障碍。目前，治疗主要集中在支持性护理方面，无论器官损伤的原因是什么，这些护理方法都是适用的。
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