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新冠肺炎患者的肺移植:迄今为止我们所学到的。

Lung Transplantation in Coronavirus-19 Patients: What We Have Learned So Far.

机构信息

Department of Thoracic Surgery, Northwestern University Feinberg School of Medicine, 676 North Saint Clair Street, Suite 650, Chicago, IL 60611, USA.

Department of Thoracic Surgery, Northwestern University Feinberg School of Medicine, 676 North Saint Clair Street, Suite 650, Chicago, IL 60611, USA.

出版信息

Clin Chest Med. 2023 Jun;44(2):347-357. doi: 10.1016/j.ccm.2022.11.017. Epub 2022 Nov 22.

Abstract

Coronavirus-19 (COVID-19) can result in irrecoverable acute respiratory distress syndrome (ARDS) or life-limiting fibrosis for which lung transplantation is currently the only viable treatment. COVID-19 lung transplantation has transformed the field of lung transplantation, as before the pandemic, few transplants had been performed in the setting of infectious disease or ARDS. Given the complexities associated with COVID-19 lung transplantation, it requires strict patient selection with an experienced multidisciplinary team in a high-resource hospital setting. Current short-term outcomes of COVID-19 lung transplantation are promising. However, follow-up studies are needed to determine long-term outcomes and whether these patients may be predisposed to unique complications.

摘要

新型冠状病毒病(COVID-19)可导致无法挽回的急性呼吸窘迫综合征(ARDS)或危及生命的纤维化,目前肺移植是唯一可行的治疗方法。COVID-19 肺移植改变了肺移植领域,因为在大流行之前,在传染病或 ARDS 背景下进行的移植手术很少。鉴于 COVID-19 肺移植的复杂性,它需要在高资源医院环境中由经验丰富的多学科团队进行严格的患者选择。COVID-19 肺移植的当前短期结果很有希望。但是,需要进行随访研究以确定长期结果以及这些患者是否可能易患独特的并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bdd0/9678827/051a69ddaeb9/gr1_lrg.jpg

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