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全生命周期的紧张症和电抽搐治疗。

Catatonia and ECT across the lifespan.

机构信息

Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, J5, 68159 Mannheim, Germany.

Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, J5, 68159 Mannheim, Germany.

出版信息

Schizophr Res. 2024 Jan;263:246-251. doi: 10.1016/j.schres.2023.04.004. Epub 2023 Apr 20.

Abstract

Electroconvulsive therapy (ECT) is a safe and effective treatment for catatonia with high response rates. Although empirical data suggest that tolerability and efficacy are at least as good as in adults, ECT treatment of children, adolescents, and geriatric patients seems to pose a specific challenge for many practitioners. This article intends to explore and discuss reasons hindering the use of ECT in these patient groups, give an overview on the use of ECT to treat catatonia and provide practical advice on ECT in children, adolescents, and geriatric patients for the treatment of catatonia. Classification of catatonia as a subform of schizophrenia and a diagnostic overlap with other common conditions in children, adolescents, and geriatric patients might lead to underdiagnosis of catatonia. Concerns about the mechanism of action and about a lack of controlled studies as well as general concerns about the use of ECT in children and adolescents might lead to underutilization of ECT. However, studies of ECT to treat catatonia in children, adolescents, and geriatric patients consistently show its safety and effectiveness. Administration of ECT needs to consider some specific characteristics of children, adolescents, and geriatric patients. In conclusion, ECT is a safe and highly effective treatment for catatonia across the lifespan. Existing evidence does not warrant restrictions of its use in certain age groups.

摘要

电抽搐治疗(ECT)是一种安全有效的治疗紧张症的方法,其应答率较高。尽管经验数据表明,其耐受性和疗效至少与成人一样好,但ECT 治疗儿童、青少年和老年患者似乎对许多从业者来说是一个特殊的挑战。本文旨在探讨和讨论在这些患者群体中使用 ECT 受到阻碍的原因,概述 ECT 治疗紧张症的情况,并就 ECT 治疗儿童、青少年和老年紧张症患者提供实用建议。将紧张症分类为精神分裂症的一种亚型,以及与儿童、青少年和老年患者的其他常见病症之间存在诊断重叠,可能导致紧张症的诊断不足。对作用机制的担忧,以及缺乏对照研究,以及对儿童和青少年使用 ECT 的普遍担忧,可能导致 ECT 的利用率不足。然而,关于儿童、青少年和老年紧张症患者的 ECT 治疗研究一致表明其安全性和有效性。ECT 的实施需要考虑到儿童、青少年和老年患者的一些特殊特征。总之,ECT 是一种安全且高度有效的治疗方法,适用于整个生命周期的紧张症。现有证据不支持在某些年龄组中限制其使用。

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