Martelli C
Quad Sclavo Diagn. 1978 Mar;14(1):26-94.
The A. describes the normal pathological proteic, immunological and cito-immunological features of synovial fluid. According to these features, the synovial fluid have been classified into 3 groups: a) non-inflammatory, animmune fluids (without pathological immunitary features); b) inflammatory, normoimmune fluids (having immunological features with normal physiopathological reactions); c) inflammatory, iperimmune-disimmune fluids (with complex and abnormal immunological features). Histologically, they correspond to: a) non flogistic artrosynovitis (synoviosis, simple synovitis); b) inflammatory arthrosynovitis without tipical features (they are also described as cronic aspecific arthorosynovitis) or characterized by pathohomonic features (tubercolar synovitis, gouty synovitis. ecc.); c) rheumatoid arthrosynovitis (and inflammatory arthrosinovitis rheumatoid like). There is a generical correlation between histological aspects of groups a) and b) and humoral values of synovial fluid. Tipical correlations have been found between histological features of RA and humoral values of synovial fluid. These are expression of individual immunological reactivity of tissues in presence of rheumatoid factors. The tissutal reactivity can subiecy even to endogenous or exogenous causes.
本文描述了滑液正常的病理蛋白质、免疫和细胞免疫特征。根据这些特征，滑液可分为3组：a）非炎性、无免疫性液体（无病理免疫特征）；b）炎性、正常免疫性液体（具有正常生理病理反应的免疫特征）；c）炎性、超免疫 - 免疫失调性液体（具有复杂和异常的免疫特征）。组织学上，它们分别对应于：a）非炎性关节滑膜炎（滑膜增生、单纯滑膜炎）；b）无典型特征的炎性关节滑膜炎（也被描述为慢性非特异性关节滑膜炎）或具有病理同源特征的炎性关节滑膜炎（结核性滑膜炎、痛风性滑膜炎等）；c）类风湿性关节滑膜炎（以及类风湿样炎性关节滑膜炎）。a组和b组的组织学特征与滑液的体液值之间存在一般相关性。在类风湿性关节炎的组织学特征与滑液的体液值之间发现了典型的相关性。这些是在存在类风湿因子的情况下组织个体免疫反应性的表现。组织反应性甚至可能受到内源性或外源性因素的影响。
