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术中细胞回收在转子下短缩截骨术治疗高位髋关节脱位全髋关节置换术中的应用:一项回顾性队列研究。

The use of intraoperative cell salvage in total hip arthroplasty with subtrochanteric shortening osteotomy for the treatment of high hip dislocation: a retrospective cohort study.

机构信息

Department of Orthopedic Surgery, West China Medical School, West China Hospital, Sichuan University, Chengdu, Sichuan Province, 610041, People's Republic of China.

West China School of Nursing, Department of Orthopedics, West China Hospital, Sichuan University, Chengdu, Sichuan Province, 610041, People's Republic of China.

出版信息

BMC Musculoskelet Disord. 2023 Apr 22;24(1):318. doi: 10.1186/s12891-023-06427-5.

Abstract

BACKGROUND

Intraoperative cell salvage (ICS) is an important component of blood management in patients undergoing orthopedic surgery. However, the role of ICS is less well defined in total hip arthroplasty (THA) with subtrochanteric shortening osteotomy (SSO) which is a common surgical technique to manage high hip dislocation. This study aimed to determine the effect of ICS during THA with SSO and to identify factors associated with the ability to salvage sufficient collection for reinfusion in patients with high hip dislocation.

METHODS

We identified 178 patients who underwent THA with SSO for high hip dislocation between November 2010 and April 2021. The consecutive cohort was analyzed by logistic regression to determine the effect of ICS on postoperative allogeneic blood transfusion (ABT) and to explore the associations between patient demographics, clinical and radiographic characteristics, preoperative laboratory examination, and surgical variables with the ability to generate adequate blood salvage to reinfuse.

RESULTS

In the consecutive cohort of 178 patients, cell salvage was reinfused in 107 patients (60.1%) and postoperative allogeneic red blood cell (RBC) transfusion within 3 days of implantation was administrated in 40 patients (22.5%). In multivariate analysis, the reinfusion of ICS (OR (95%CI) 0.17 (0.07-0.47)), center of rotation (COR) height ≥ 60 mm (OR (95%CI) 3.30 (1.21-9.01)), the length of SSO ≥ 30 mm (OR (95%CI) 2.75 (1.05-7.22)) and the use of drainage (OR (95%CI) 2.28 (1.04-5.03)) were identified as independent factors of postoperative allogeneic RBC transfusion. In addition, the following variables were identified as independent factors associated with the ability to generate sufficient blood salvage volume for reinfusion: COR height ≥ 60 mm (OR (95%CI) 3.47 (1.58-7.61)), limb-length discrepancy (LLD) ≥ 25 mm (OR (95%CI) 2.55 (1.15-5.65)) and length of SSO ≥ 30 mm (OR (95%CI) 2.75 (1.33-5.69)).

CONCLUSIONS

ICS was efficacious in reducing the exposure rate of postoperative RBC transfusion for high hip dislocation during THA with SSO. In addition, patients with greater COR height, larger LLD, and longer length of SSO were predisposed to generate sufficient collection for reinfusion in THA with SSO.

摘要

背景

术中细胞回收(ICS)是骨科手术患者血液管理的重要组成部分。然而,在伴有转子下缩短截骨术(SSO)的全髋关节置换术(THA)中,ICS 的作用尚未得到明确界定,SSO 是一种常见的手术技术,用于治疗高位髋关节脱位。本研究旨在确定 ICS 在伴有 SSO 的 THA 中的作用,并确定与能够回收足够的血液进行再输注相关的因素,以满足高位髋关节脱位患者的需求。

方法

我们回顾性分析了 2010 年 11 月至 2021 年 4 月期间 178 例因高位髋关节脱位行 THA 合并 SSO 的患者。通过逻辑回归分析连续队列,以确定 ICS 对术后同种异体输血(ABT)的影响,并探讨患者人口统计学、临床和影像学特征、术前实验室检查以及手术变量与能够产生足够的血液回收量进行再输注之间的关联。

结果

在 178 例连续队列患者中,107 例(60.1%)进行了 ICS 再输注,40 例(22.5%)在植入后 3 天内接受了同种异体红细胞(RBC)输血。多变量分析显示,ICS 再输注(OR(95%CI)0.17(0.07-0.47))、旋转中心(COR)高度≥60mm(OR(95%CI)3.30(1.21-9.01))、SSO 长度≥30mm(OR(95%CI)2.75(1.05-7.22))和引流的使用(OR(95%CI)2.28(1.04-5.03))是术后异体 RBC 输血的独立因素。此外,以下变量被确定为与能够产生足够的血液回收量进行再输注相关的独立因素:COR 高度≥60mm(OR(95%CI)3.47(1.58-7.61))、肢体长度差异(LLD)≥25mm(OR(95%CI)2.55(1.15-5.65))和 SSO 长度≥30mm(OR(95%CI)2.75(1.33-5.69))。

结论

ICS 可有效降低伴有转子下缩短截骨术的 THA 治疗高位髋关节脱位患者术后 RBC 输血的暴露率。此外,COR 高度较高、LLD 较大和 SSO 长度较长的患者在接受 SSO 合并 THA 时更倾向于产生足够的回收量进行再输注。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6fe8/10122396/47d4456dd38e/12891_2023_6427_Figa_HTML.jpg

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