Research and Evaluation, UK Health Security Agency, UK.
Research and Evaluation, UK Health Security Agency, UK.
Virology. 2023 Jun;583:27-28. doi: 10.1016/j.virol.2023.04.006. Epub 2023 Apr 17.
Surfaces contaminated with infectious SARS-CoV-2 particles have the potential to cause human infection and any increase in surface survivability of a SARS-CoV-2 variant may increase its prevalence over other variants. This study investigated whether there were differences in surface persistence between Delta and Omicron variants leading to Omicron's dominance globally. Stainless steel coupons were inoculated with suspensions of either Delta or Omicron variant and exposed to typical environmental conditions within a containment level 3 laboratory. Coupons were recovered at different timepoints and enumerated using plaque assay. Both variants were recoverable for >48 h on the coupons. Omicron showed a greater reduction of viability after 48 h compared to Delta with a 20-fold decrease versus 15-fold respectively, but this difference was not statistically significant (p = 0.424). These results indicate that Omicron's surface persistence is unlikely to contribute to it becoming the dominant variant over Delta.
表面污染有传染性 SARS-CoV-2 颗粒的物体有可能导致人类感染,SARS-CoV-2 变体在表面上的存活能力任何增加都可能使其在其他变体中更为流行。本研究旨在调查德尔塔和奥密克戎变体之间在表面持久性方面是否存在差异,从而导致奥密克戎在全球的优势地位。不锈钢试片用德尔塔或奥密克戎变体的悬浮液接种,并在三级实验室的典型环境条件下暴露。在不同时间点回收试片并用噬斑法进行计数。两种变体在试片上的可恢复性均超过 48 小时。奥密克戎变体在 48 小时后显示出比德尔塔变体更大的存活能力下降,分别下降了 20 倍和 15 倍,但这一差异没有统计学意义(p = 0.424)。这些结果表明,奥密克戎在表面上的持久性不太可能导致其成为德尔塔变体的优势变体。