Bursa Uludağ University Faculty of Medicine, Department of Ophthalmology, Bursa, Türkiye.
Bursa Uludağ University Faculty of Medicine, Department of Pulmonology, Bursa, Türkiye.
Turk J Ophthalmol. 2023 Apr 20;53(2):124-129. doi: 10.4274/tjo.galenos.2022.36930.
Coronavirus disease 2019 (COVID-19) is a procoagulant disease that increases the risk of clinically evident thrombotic complications. Herein we present 3 cases with different retinal artery occlusions that emerged soon after the diagnosis of COVID-19. The first patient had central retinal artery occlusion (CRAO) that resulted in visual loss in one eye. The second patient had inflammatory peripheral retinal artery occlusion, vasculitis, and uveitis which did not affect vision. The third patient presented with CRAO following the progression from orbital cellulitis to orbital apex syndrome. Interestingly, CRAO progressed to internal carotid artery occlusion in this case within days and resulted in monocular visual loss. Variations in the underlying pathophysiology and the characteristics of individual immune responses in patients with COVID-19 may be factors that determine differences in clinical manifestations. This article aims to describe different presentations of COVID-19-related retinal artery occlusions and discuss possible pathophysiological aspects.
新型冠状病毒肺炎（COVID-19）是一种促凝疾病，会增加临床明显血栓并发症的风险。在此，我们介绍了 3 例不同的视网膜动脉阻塞病例，这些病例均在 COVID-19 诊断后不久出现。第一例患者发生了中央视网膜动脉阻塞（CRAO），导致一只眼睛视力丧失。第二例患者出现了炎症性周边视网膜动脉阻塞、血管炎和葡萄膜炎，但未影响视力。第三例患者表现为从眼眶蜂窝织炎进展为眶尖综合征后发生 CRAO。有趣的是，在这种情况下，CRAO 在数天内进展为颈内动脉阻塞，导致单眼视力丧失。COVID-19 患者潜在病理生理学的变化和个体免疫反应的特征可能是决定临床表现差异的因素。本文旨在描述 COVID-19 相关视网膜动脉阻塞的不同表现，并讨论可能的病理生理学方面。
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