Hasani-Ranjbar Shirin, Razmandeh Rezvan, Ghodssi-Ghassemabadi Robabeh, Khodabakhshi Marjan, Ebrahimpour Mahbube
Obesity and Eating Habits Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Department of Biostatistics, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
Iran J Public Health. 2023 Feb;52(2):420-426. doi: 10.18502/ijph.v52i2.11895.
Calculating and predicting the risk of disease plays an important role in preventive medicine. Today, some risk scores have been designed to estimate the risk of cardiovascular diseases (CVDs) by assessing different factors. Obesity is associated with an increased risk of cardiovascular disease, so we decided to calculate the possible risk of heart disease in obese Iranian people to suggest a more accurate calculator.
In this cross-sectional study, we compared the data of 289 people from Framingham Risk Score and ASCVD Risk Score calculations who had been referred to Shariati Hospital Obesity Clinic, Tehran, Iran from 2016 to 2019. In the form of sub-goals, we examined other factors such as blood pressure and hepatic aminotransferases, etc.
The mean age of participants was 51.20±7.58 years, 86.2% being women. Of the whole, 19.72%, 31.83%, 21.11%, and 27.34% were categorized as overweight, Obese I, II, and III, respectively. According to the ASCVD score 80.3%, 4.8%, and 14.9%, and according to the Framingham score 95.5%, 3.5%, and 1% were classified as low-risk, intermediate-risk, and high-risk. Moreover, a fair agreement was observed between the two-risk score in the whole (Kappa=0.236; <0.001), overweight (Kappa=0.304; =0.028), Obese I (Kappa=0.210; =0.048), Obese II (Kappa=0.268; =0.015), and obese III (Kappa=0.202; =0.023).
Despite its age limit, ASCVD has a higher risk of CVDs, causing statin care (which has a protective role for cardiovascular disease) to be given to a larger population.
计算和预测疾病风险在预防医学中起着重要作用。如今，一些风险评分已被设计用于通过评估不同因素来估计心血管疾病（CVD）的风险。肥胖与心血管疾病风险增加相关，因此我们决定计算肥胖伊朗人群患心脏病的可能风险，以提出更准确的计算器。
在这项横断面研究中，我们比较了2016年至2019年转诊至伊朗德黑兰沙里亚蒂医院肥胖诊所的289人的弗明汉风险评分和ASCVD风险评分计算数据。以子目标的形式，我们检查了其他因素，如血压和肝转氨酶等。
参与者的平均年龄为51.20±7.58岁，86.2%为女性。总体中，分别有19.72%、31.83%、21.11%和27.34%被归类为超重、肥胖I级、II级和III级。根据ASCVD评分，80.3%、4.8%和14.9%以及根据弗明汉评分分别为95.5%、3.5%和1%被分类为低风险、中风险和高风险。此外，在总体（Kappa = 0.236；<0.001）、超重（Kappa = 0.304；= 0.028）、肥胖I级（Kappa = 0.210；= 0.048）、肥胖II级（Kappa = 0.268；= 0.015）和肥胖III级（Kappa = 0.202；= 0.023）中，两种风险评分之间观察到适度的一致性。
尽管有年龄限制，但ASCVD的CVD风险更高，导致他汀类药物治疗（对心血管疾病有保护作用）应用于更多人群。
