Bampidis Vasileios, Azimonti Giovanna, Bastos Maria de Lourdes, Christensen Henrik, Dusemund Birgit, Fašmon Durjava Mojca, Kouba Maryline, López-Alonso Marta, López Puente Secundino, Marcon Francesca, Mayo Baltasar, Pechová Alena, Petkova Mariana, Ramos Fernando, Sanz Yolanda, Villa Roberto Edoardo, Woutersen Ruud, Pagés Plaza Daniel, Ortuño Casanova Jordi
EFSA J. 2023 Apr 20;21(4):e07973. doi: 10.2903/j.efsa.2023.7973. eCollection 2023 Apr.
Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the efficacy of 6-phytase produced by the genetically modified strain CGMCC 12056 (APSA PHYTAFEED® 20,000 GR/L) as a zootechnical feed additive (functional group: digestibility enhancers) for pigs for fattening at a minimum recommended level of 1,000 U /kg feed. In a previous assessment, three trials were submitted; one of them showed significant improvements on zootechnical parameters supporting the efficacy of the additive. The other two trials evaluating apparent faecal phosphorus digestibility and bone mineralisation, showed no improvements on phosphorus retention in bone and, therefore, the FEEDAP Panel could not conclude on the efficacy of the additive. The applicant submitted two new efficacy studies in pigs for fattening evaluating the animal's zootechnical performance, apparent faecal phosphorus digestibility and bone mineralisation. One of the trials was not considered due to high rates of mortality, culling of animals and medical treatments applied. In the other trial, significant improvements on final body weight and apparent total track phosphorus digestibility were found in the animals that received the phytase at 1,000 U/kg complete feed. Owing to the lack of sufficient data, the FEEDAP Panel could not conclude on the efficacy of the additive in pigs for fattening.
应欧盟委员会的要求，欧洲食品安全局（EFSA）被要求就转基因菌株CGMCC 12056（APSA PHYTAFEED® 20,000 GR/L）生产的6-植酸酶作为育肥猪动物营养饲料添加剂（功能类别：消化率提高剂）在最低推荐水平1,000 U/kg饲料时的功效发表科学意见。在之前的评估中，提交了三项试验；其中一项试验显示动物营养参数有显著改善，支持该添加剂的功效。另外两项评估表观粪便磷消化率和骨矿化的试验显示，骨中磷的保留没有改善，因此，饲料添加剂和动物营养产品专家委员会无法就该添加剂的功效得出结论。申请人提交了两项新的育肥猪功效研究，评估动物的动物营养性能、表观粪便磷消化率和骨矿化。其中一项试验由于高死亡率、动物淘汰率和所用药物治疗而未被考虑。在另一项试验中，在接受1,000 U/kg全价饲料植酸酶的动物中，发现终末体重和表观总磷消化率有显著改善。由于缺乏足够的数据，饲料添加剂和动物营养产品专家委员会无法就该添加剂对育肥猪的功效得出结论。
