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"Chromatolytic" neurons in lateral geniculate body in Werdnig-Hoffmann disease.

作者信息

Peress N S, Stermann A B, Miller R, Kaplan C G, Little B W

出版信息

Clin Neuropathol. 1986 Mar-Apr;5(2):69-72.

PMID:3708955
Abstract

In a case of Werdnig-Hoffmann disease, we have observed pathologic changes in the neuronal cell bodies of the lateral geniculate nucleus. These changes are similar to those seen in lower motor neurons and dorsal root ganglia. As the lateral geniculate nucleus and its projections are entirely central, this observation raises questions as to the possible etiologic role of root entry zone glial bundles in the evolution of neuronal alterations in severe spinal muscular atrophy.

摘要

相似文献

1
"Chromatolytic" neurons in lateral geniculate body in Werdnig-Hoffmann disease.
Clin Neuropathol. 1986 Mar-Apr;5(2):69-72.
2
Sensory ganglioneuropathy in infantile spinal muscular atrophy. Light and electronmicroscopic findings in two cases.
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3
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[Infantile progressive spinal muscular atrophy. Werdnig-Hoffmann disease].[婴儿进行性脊髓性肌萎缩症。韦尼克-霍夫曼病]
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引用本文的文献

1
Spinal muscular atrophy: journeying from bench to bedside.脊髓性肌萎缩症:从实验室到临床的历程
Neurotherapeutics. 2014 Oct;11(4):786-95. doi: 10.1007/s13311-014-0293-y.
2
Chromatolytic neurons in Werdnig-Hoffmann disease contain phosphorylated neurofilaments.韦尼克-霍夫曼病中的染色质溶解神经元含有磷酸化神经丝。
Acta Neuropathol. 1988;77(1):91-4. doi: 10.1007/BF00688247.
3
Ubiquitin and phosphorylated neurofilament epitopes in ballooned neurons of the extraocular muscle nuclei in a case of Werdnig-Hoffmann disease.
Acta Neuropathol. 1990;80(3):334-7. doi: 10.1007/BF00294653.