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阿达木单抗治疗的患者接种两剂BBIBP-CorV疫苗后泛发性脓疱型银屑病发作:一例报告

Generalized Pustular Psoriasis Flare-Up after Both Doses of BBIBP-CorV Vaccination in a Patient under Adalimumab Treatment: A Case Report.

作者信息

Dayani Dorsa, Rokhafrouz Hatam, Balighi Kamran

机构信息

School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.

Autoimmune Bullous Diseases Research Center, Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran.

出版信息

Case Rep Dermatol. 2023 Apr 19;15(1):61-65. doi: 10.1159/000530074. eCollection 2023 Jan-Dec.

DOI:10.1159/000530074
PMID:37089907
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10116389/
Abstract

Generalized pustular psoriasis is a possibly serious condition that can be triggered by various factors. Previous studies show a slight likelihood of disease exacerbation subsequent to COVID-19 vaccination. Here, we present the first (to the best of our knowledge) case of pustular psoriasis flare after each one of the two shots of the BBIBP-CorV (Sinopharm) vaccine despite adalimumab treatment.

摘要

泛发性脓疱型银屑病是一种可能较为严重的疾病,可由多种因素引发。既往研究表明,接种新冠病毒疫苗后疾病有轻微加重的可能性。在此,我们(据我们所知)首次报告了一例在接受阿达木单抗治疗的情况下,接种两剂BBIBP-CorV(国药集团)疫苗后每次均出现脓疱型银屑病发作的病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a61b/10116389/4936b36910e5/cde-2023-0015-0001-530074_F03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a61b/10116389/d1ef06c6265b/cde-2023-0015-0001-530074_F01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a61b/10116389/51591c064c05/cde-2023-0015-0001-530074_F02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a61b/10116389/4936b36910e5/cde-2023-0015-0001-530074_F03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a61b/10116389/d1ef06c6265b/cde-2023-0015-0001-530074_F01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a61b/10116389/51591c064c05/cde-2023-0015-0001-530074_F02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a61b/10116389/4936b36910e5/cde-2023-0015-0001-530074_F03.jpg

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J Eur Acad Dermatol Venereol. 2022 May;36(5):e330-e332. doi: 10.1111/jdv.17918. Epub 2022 Jan 28.
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