抗逆转录病毒治疗的成年艾滋病毒阳性患者中的营养过剩及其相关因素，埃塞俄比亚西北部。

Overnutrition and its associated factors among adult human immunodeficiency virus positive patients on antiretroviral therapy, Northwest, Ethiopia.

机构信息

Department of Nursing, College of Health Science, Debre Berhan University, Debre Berhan, Ethiopia.

Department of Nursing, College of Health Science, Wolkite University, Wolkite, Ethiopia.

出版信息

Afr Health Sci. 2022 Dec;22(4):452-460. doi: 10.4314/ahs.v22i4.51.

DOI:10.4314/ahs.v22i4.51

PMID:37092083

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10117498/

Abstract

BACKGROUND

Anti-retroviral therapy was introduced to treat human immunodeficiency virus patients; comorbidities affecting individuals with human immunodeficiency virus-positive have changed dramatically, with increasing the prevalence of overnutrition. Overnutrition has increased from time to time in people living with the human immunodeficiency virus. However, there is scarce adequate documented evidence regarding nutrition on human immunodeficiency virus.

OBJECTIVE

The study aimed to assess the magnitude of over nutrition and its associated factors among human immunodeficiency virus receiving antiretroviral therapy.

METHODS

We used a cross-sectional study design to collect data from 422 participants from Debre Markos hospital. We used a systematic sampling technique to select the total number of participants. The outcomes of Data were entered, and coded using Epi-data version 4.1 and analysed using STATA Version 14.1. We performed a multivariable logistic regression model to identify determinants of over-nutrition at a p-value of less than 0.05.

RESULTS

The magnitude of overnutrition was 19.7% (95%CI: 14.6-25.4). Age group > 45 years (AOR: 3.18:95%CI: 1.09, 9.22), being farmer (AOR: 0.068, 95%CI (0.007, 0.611), family size greater than or equal to 4 (AOR: 3.18:95%CI (1.09-9.22), viral load less than 1000 copies/ml (AOR: 4.45 95%CI (1.69-11.76), and use of prophylaxis therapy (AOR: 2.67:95%CI (1.138-6.291) were significantly associated with over nutrition.

CONCLUSIONS

In this study one-fifth of Human Immunodeficiency Virus/Acquired Immunodeficiency Virus patients had over nutrition. In this study, the magnitude of overnutrition is high associated with a viral load of fewer than 1000 copies/cell, age greater than 45, and having taken prophylaxis therapy. Therefore, education about lifestyle change, regular monitoring of weight, regular nutritional assessment, and intervention of the existed problems like doing regular exercise is highly recommended.

摘要

背景

抗逆转录病毒疗法被引入以治疗人类免疫缺陷病毒患者；影响人类免疫缺陷病毒阳性个体的合并症发生了巨大变化，超重的患病率不断增加。超重现象在人类免疫缺陷病毒感染者中时有发生。然而，关于人类免疫缺陷病毒的营养问题，证据不足。

目的

本研究旨在评估接受抗逆转录病毒治疗的人类免疫缺陷病毒患者中营养过剩的程度及其相关因素。

方法

我们采用横断面研究设计，从德布雷马科斯医院收集了 422 名参与者的数据。我们使用系统抽样技术选择了总人数。数据结果输入并使用 Epi-data 版本 4.1 进行编码，使用 STATA 版本 14.1 进行分析。我们进行了多变量逻辑回归模型分析，以确定营养过剩的决定因素，p 值小于 0.05。

结果

营养过剩的程度为 19.7%（95%CI：14.6-25.4）。年龄组>45 岁（AOR：3.18：95%CI：1.09，9.22）、农民（AOR：0.068，95%CI（0.007，0.611））、家庭人数≥4 人（AOR：3.18：95%CI（1.09-9.22））、病毒载量<1000 拷贝/ml（AOR：4.45 95%CI（1.69-11.76））和使用预防疗法（AOR：2.67：95%CI（1.138-6.291））与营养过剩显著相关。