肝硬化患者身体成分评估方法及其营养研究的范围综述。
A scoping review of the methods used in patients with liver cirrhosis to assess body composition and their nutritional findings.
机构信息
Laboratory for Proteomics and Metabolomics, Research Division, Hospital General de Mexico "Dr Eduardo Liceaga,", 06720, Mexico City, Mexico.
Department of Nursing and Obstetrics, Universidad de Guanajuato, 36000, Celaya City, Mexico.
出版信息
Eur J Clin Nutr. 2023 Sep;77(9):845-854. doi: 10.1038/s41430-023-01287-7. Epub 2023 Apr 24.
BACKGROUND AND OBJECTIVES
Body composition (BC) assessment in cirrhosis has a wide variety of methods with no consensus on the best tools for each body component in patients with Liver Cirrhosis (LC). We aimed to conduct a systematic scoping review of the most frequent body composition analysis methods and nutritional findings published in liver cirrhosis patients.
METHODS
We searched for articles in PubMed, Scopus, and ISI Web of Science databases. Keywords selected the BC methods and parameters in LC.
RESULTS
Eleven methods were found. The most frequently used were computed tomography (CT) 47.5%, Bioimpedance Analysis 35%, DXA 32.5%, and anthropometry 32.5%. Up to 15 BC parameters were reported from each method.
CONCLUSIONS
The vast heterogeneity in the results found during the qualitative analysis and imaging methods must reach a consensus to achieve a better clinical practice and improve nutritional treatment, as the physiopathology in LC compromises the nutritional status directly.
背景与目的
肝硬化患者的身体成分（BC）评估方法多种多样，对于肝硬化（LC）患者的每个身体成分，尚无共识认为哪种工具最好。我们旨在对发表在肝硬化患者中的最常见的身体成分分析方法和营养研究进行系统的范围综述。
方法
我们在 PubMed、Scopus 和 ISI Web of Science 数据库中搜索了文章。选择了 BC 方法和 LC 中的参数作为关键词。
结果
发现了 11 种方法。最常用的是计算机断层扫描（CT）47.5%，生物阻抗分析 35%，双能 X 线吸收法（DXA）32.5%和人体测量学 32.5%。每种方法报告的 BC 参数多达 15 个。
结论
定性分析和影像学方法中发现的结果存在很大的异质性，必须达成共识，以实现更好的临床实践和改善营养治疗，因为 LC 的病理生理学直接影响营养状况。
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