Brufani M, Marta M, Pomponi M
Eur J Biochem. 1986 May 15;157(1):115-20. doi: 10.1111/j.1432-1033.1986.tb09646.x.
The anticholinesterase activity of a new carbamate, heptylphysostigmine, was studied in vitro. This compound is a competitive inhibitor of acetylcholinesterase (or true cholinesterase) having Ki = (1 +/- 0.5) X 10(-7) M. The inhibition was instantaneous at the onset and did not diminish with prolonged incubation of the drug and enzyme.
在体外研究了一种新型氨基甲酸酯——庚基毒扁豆碱的抗胆碱酯酶活性。该化合物是乙酰胆碱酯酶（或真性胆碱酯酶）的竞争性抑制剂，其抑制常数Ki = (1 ± 0.5)×10⁻⁷M。抑制作用在开始时是瞬间发生的，并且不会随着药物和酶的长时间孵育而减弱。
