Department of Orthopedic Surgery, Section of Orthopedic Oncology, Rush University Medical Center, Chicago, Illinois, USA.
Colorado Limb Consultants, Denver, Colorado, USA.
J Surg Oncol. 2023 Aug;128(2):359-366. doi: 10.1002/jso.27284. Epub 2023 Apr 24.
Pathologic fractures of the pelvis/sacrum due to metastatic bone disease (MBD) cause pain and dysfunction due to mechanical instability of the pelvic ring. This study presents our multi-institutional experience with percutaneous stabilization of pathologic fractures and osteolytic lesions from MBD throughout the pelvic ring.
The records of patients undergoing this procedure from 2018 to 2022 were reviewed retrospectively from two institutions. Surgical data and functional outcomes were recorded.
Fifty-six patients underwent percutaneous stabilization, with a median operative duration of 119 min (interquartile range [IQR]: 92.8, 167) and median estimated blood loss of 50 mL (IQR: 20, 100). The median length of stay was 3 days (IQR: 1, 6), and 69.6% (n = 39) of patients were discharged home. Early complications included one partial lumbosacral plexus injury, three acute kidney injuries, and one case of intra-articular cement extravasation. Late complications included two infections and one revision stabilization procedure for hardware failure. Mean Eastern Cooperative Oncology Group (ECOG) scores improved from 3.02 (SD 0.8) preoperatively to 1.86 (SD 1.1) postoperatively (p < 0.001). Ambulatory status also improved (p < 0.001).
Percutaneous stabilization of pathologic fractures and osteolytic defects of the pelvis and sacrum is a procedure that improves patient function, ambulatory status and is associated with a limited complication profile.
转移性骨病(MBD)导致骨盆/骶骨病理性骨折会引起骨盆环机械不稳定导致的疼痛和功能障碍。本研究介绍了我们多机构在整个骨盆环中对 MBD 引起的病理性骨折和溶骨性病变进行经皮稳定的经验。
回顾性分析了 2018 年至 2022 年期间在两个机构接受该手术的患者的记录。记录手术数据和功能结果。
56 例患者接受了经皮稳定治疗,中位手术时间为 119 分钟(四分位距 [IQR]:92.8,167),中位估计失血量为 50 毫升(IQR:20,100)。中位住院时间为 3 天(IQR:1,6),69.6%(n=39)的患者出院回家。早期并发症包括 1 例部分腰骶丛神经损伤、3 例急性肾损伤和 1 例关节内水泥外渗。晚期并发症包括 2 例感染和 1 例因内固定失败而进行的翻修稳定手术。术前东部合作肿瘤学组(ECOG)评分均值为 3.02(标准差 0.8),术后为 1.86(标准差 1.1)(p<0.001)。活动能力也得到改善(p<0.001)。
经皮稳定治疗骨盆和骶骨病理性骨折和溶骨性缺损是一种改善患者功能、活动能力的方法,且并发症发生率较低。