Wiedemann H R, Drescher J
Eur J Pediatr. 1986 Apr;144(6):579-82. doi: 10.1007/BF00496040.
The lacrimo-auriculo-dento-digital or LADD syndrome is a true multiple congenital anomalies (MCA) syndrome characterized by hypoplasias, aplasias or atresias in the lacrimal system; anomalies of the ears and hearing loss; hypoplasias, aplasias or atresias in the region of the salivary system; dental anomalies; and digital malformations. The syndrome is thought to be an autosomal dominant trait with variable expressivity. It seems to be rare. Two new cases are reported and the clinical spectrum of the syndrome is reviewed. The paediatrician who is responsible for the child as a whole individual should know the LADD syndrome. Its early recognition may be important.
泪腺-耳-齿-指综合征（LADD综合征）是一种典型的多发性先天性畸形（MCA）综合征，其特征为泪腺系统发育不全、发育不良或闭锁；耳部异常及听力丧失；唾液腺系统区域发育不全、发育不良或闭锁；牙齿异常；以及手指畸形。该综合征被认为是一种具有可变表达性的常染色体显性性状。它似乎很罕见。本文报告了两例新病例，并对该综合征的临床谱进行了综述。负责儿童整体健康的儿科医生应该了解LADD综合征。早期识别可能很重要。
