二尖瓣重度瓣环钙化的二尖瓣疾病微创治疗：2022年二尖瓣专题会议论文
Minimally invasive treatment of mitral valve disease with severe mitral annular calcification: Meeting paper for Mitral Conclave 2022.
作者信息
Wisneski Andrew D, Hamilton Barbara, Nguyen Tom C
机构信息
Division of Cardiothoracic Surgery, Department of Surgery, University of California San Francisco, San Francisco, Calif.
出版信息
JTCVS Tech. 2022 Dec 7;18:44-50. doi: 10.1016/j.xjtc.2022.11.008. eCollection 2023 Apr.
OBJECTIVE
Mitral valve disease in presence of severe mitral annular calcification (MAC) remains a challenge for surgeons to address. Conventional surgical techniques have potential for heightened morbidity and mortality. The advent of transcatheter heart valve technology and transcatheter mitral valve replacement (TMVR) holds promise to treat mitral valve disease with MAC with excellent clinical outcomes.
METHODS
We review current treatment strategies for MAC and studies in which TMVR techniques were used.
RESULTS
Several studies and a global registry describe outcomes of TMVR for mitral valve disease with MAC. We describe our specific technique on how to perform a minimally invasive transatrial approach for TMVR.
CONCLUSIONS
TMVR demonstrates strong promise as a safe and effective way to treat mitral valve disease with MAC. We advocate for a minimally invasive transatrial approach when performing TMVR for mitral valve disease with MAC.
目的
存在严重二尖瓣环钙化（MAC）的二尖瓣疾病仍然是外科医生面临的一项挑战。传统手术技术有导致发病率和死亡率升高的风险。经导管心脏瓣膜技术及经导管二尖瓣置换术（TMVR）的出现有望为伴有MAC的二尖瓣疾病带来出色的临床治疗效果。
方法
我们回顾了目前针对MAC的治疗策略以及使用TMVR技术的研究。
结果
多项研究及一项全球注册研究描述了TMVR治疗伴有MAC的二尖瓣疾病的结果。我们介绍了如何采用微创经心房入路进行TMVR的具体技术。
结论
TMVR作为一种安全有效的治疗伴有MAC的二尖瓣疾病的方法展现出巨大潜力。我们主张在对伴有MAC的二尖瓣疾病进行TMVR时采用微创经心房入路。
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