Huang Tianhai, Zou Quchao, Chu Yonghua, Jin Jinjiang, Chen Changjun
Department of Clinical Medical Engineering, Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, 310009.
Zhongguo Yi Liao Qi Xie Za Zhi. 2023 Feb 8;47(2):178-184. doi: 10.3969/j.issn.1671-7104.2023.02.012.
The emergence of smart phones has not only brought extensive changes to people's way of life, but also provided a new research platform for the expansion and application of science and technology. Technicians have combined immunoassay methods with smart phone sensing technology to develop a variety of smartphone-based biological sample analysis and detection sensing systems, promoting the application of immunoassay methods in POCT fields. In this review, we summarize the researches and applications of smart-phone in the field of immune analysis. According to the different sensors and detection objects, these applications can be divided into four aspects: camera-based spectrometer, camera-based enzyme reader, camera-based strip reader and spectrophotometer based on environmental light sensor. This study also briefly discusses some limitations of current smart phone application in immune analysis, and prospects the future applicability of smart phone sensing system.
智能手机的出现不仅给人们的生活方式带来了广泛变化,也为科技的拓展与应用提供了新的研究平台。技术人员将免疫分析方法与智能手机传感技术相结合,开发出了多种基于智能手机的生物样本分析与检测传感系统,推动了免疫分析方法在即时检验(POCT)领域的应用。在本综述中,我们总结了智能手机在免疫分析领域的研究与应用。根据不同的传感器和检测对象,这些应用可分为四个方面:基于摄像头的光谱仪、基于摄像头的酶标仪、基于摄像头的试纸条读数仪以及基于环境光传感器的分光光度计。本研究还简要讨论了当前智能手机在免疫分析应用中的一些局限性,并对智能手机传感系统未来的适用性进行了展望。