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操纵子调节 在 中的生理功能和致龋毒力。

operon regulates physiological function and cariogenic virulence in .

机构信息

Fujian Key Laboratory of Oral Diseases & Fujian Provincial Engineering Research Center of Oral Biomaterial & Stomatological Key lab of Fujian College & University, School & Hospital of Stomatology, Fujian Medical University, Fuzhou, China.

Stomatological Hospital, Southern Medical University, Guangzhou, China.

出版信息

Future Microbiol. 2023 Mar;18:225-233. doi: 10.2217/fmb-2022-0165. Epub 2023 Apr 25.

Abstract

is one of the major cariogenic pathogens in the oral cavity. The operon is responsible for the process of D-alanylation of lipoteichoic acid and is related to the virulence of . The operon contributes to the adhesion, biofilm formation, stress response, interspecies competitiveness and autolysis of . In addition, we have summarized the possible regulatory networks of the operon. This review highlights the significant role of the operon in and provides new ideas for ecological caries prevention.

摘要

是口腔中主要的致龋病原菌之一。操纵子负责脂磷壁酸的 D-丙氨酸化过程,与的毒力有关。操纵子有助于的黏附、生物膜形成、应激反应、种间竞争和自溶。此外,我们总结了操纵子的可能调控网络。本综述强调了操纵子在中的重要作用,并为生态防龋提供了新的思路。

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