Fujian Key Laboratory of Oral Diseases & Fujian Provincial Engineering Research Center of Oral Biomaterial & Stomatological Key lab of Fujian College & University, School & Hospital of Stomatology, Fujian Medical University, Fuzhou, China.
Stomatological Hospital, Southern Medical University, Guangzhou, China.
Future Microbiol. 2023 Mar;18:225-233. doi: 10.2217/fmb-2022-0165. Epub 2023 Apr 25.
is one of the major cariogenic pathogens in the oral cavity. The operon is responsible for the process of D-alanylation of lipoteichoic acid and is related to the virulence of . The operon contributes to the adhesion, biofilm formation, stress response, interspecies competitiveness and autolysis of . In addition, we have summarized the possible regulatory networks of the operon. This review highlights the significant role of the operon in and provides new ideas for ecological caries prevention.
是口腔中主要的致龋病原菌之一。操纵子负责脂磷壁酸的 D-丙氨酸化过程,与的毒力有关。操纵子有助于的黏附、生物膜形成、应激反应、种间竞争和自溶。此外,我们总结了操纵子的可能调控网络。本综述强调了操纵子在中的重要作用,并为生态防龋提供了新的思路。