在离子液体中设计蛋白质纳米结构：提高应激下细胞色素的功效。
Designing protein nano-construct in ionic liquid: a boost in efficacy of cytochrome under stresses.
机构信息
Centre for Nano and Material Sciences, Jain (Deemed-to-be University), Jain Global Campus, Kanakapura, Bangalore, Karnataka, 562112, India.
Institute of Plant Genetics (IPG), Polish Academy of Sciences, Strzeszynska 34, 60-479 Poznan, Poland.
出版信息
Chem Commun (Camb). 2023 May 11;59(39):5894-5897. doi: 10.1039/d3cc00644a.
Herein, we present a simple approach to fabricate protein nanoconstructs by complexing cytochrome (Cyt ) with silk nanofibrils (SNF) and choline dihydrogen phosphate ionic liquid (IL). The peroxidase activity of the IL modified Cyt nanoconstruct (Cyt + SNF + IL) increased significantly (2.5 to 10-fold) over unmodified Cyt and showed enhanced catalytic activity and stability under harsh conditions, proving its potential as a suitable protein packaging strategy.
在这里，我们提出了一种简单的方法来通过将细胞色素（Cyt ）与丝素纳米纤维（SNF）和磷酸二氢胆碱离子液体（IL）复合来制备蛋白质纳米结构。IL 修饰的 Cyt 纳米结构（Cyt + SNF + IL）的过氧化物酶活性明显增加（2.5 至 10 倍），与未修饰的 Cyt 相比，在恶劣条件下显示出增强的催化活性和稳定性，证明了它作为一种合适的蛋白质包装策略的潜力。
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