Department of Orthopedic Surgery, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan.
Department of Orthopedics, University of Santo Tomas Hospital, Manila, Philippines.
Anticancer Res. 2023 May;43(5):2127-2133. doi: 10.21873/anticanres.16374.
BACKGROUND/AIM: Amputation is still a viable option for musculoskeletal tumors that are multi-compartmental, adjacent to neurovascular structures, and involving pathological fractures. Complications such as poor surgical margins, local recurrence and infection after limb salvage surgery are also indications for secondary amputation. An effective hemostatic technique is vital for preventing complications of massive blood loss and prolonged operative time. The use of LigaSure™ in the field of musculoskeletal oncology has not been well documented.
This retrospective study included 27 patients with musculoskeletal tumor who underwent amputation using either LigaSure™ system (n=12) or traditional hemostatic technique (n=15) from 1999 to 2020. The purpose of this study was to evaluate the effect of LigaSure™ in terms of intra-operative blood loss, blood transfusion rates, and duration of surgery.
The use of LigaSure™ resulted in a significant decrease in intraoperative blood loss (p=0.027) and blood transfusion rates (p=0.020). There was no significant difference for the duration of surgery between the two groups (p=0.634).
The LigaSure™ system can potentially improve clinical outcomes in patients with musculoskeletal tumor undergoing amputation surgeries. The LigaSure™ system is a safe and effective hemostatic tool for musculoskeletal tumor amputation surgeries.
背景/目的:对于多腔室、临近神经血管结构和涉及病理性骨折的肌肉骨骼肿瘤,截肢仍然是一种可行的选择。保肢手术后出现手术切缘不良、局部复发和感染等并发症也是进行二次截肢的指征。有效的止血技术对于预防大量失血和手术时间延长的并发症至关重要。LigaSure™ 在肌肉骨骼肿瘤领域的应用尚未得到充分记录。
本回顾性研究纳入了 1999 年至 2020 年间接受截肢手术的 27 例肌肉骨骼肿瘤患者,其中 12 例使用 LigaSure™ 系统,15 例使用传统止血技术。本研究旨在评估 LigaSure™ 在术中失血量、输血率和手术时间方面的效果。
使用 LigaSure™ 显著减少了术中失血量(p=0.027)和输血率(p=0.020)。两组手术时间无显著差异(p=0.634)。
LigaSure™ 系统可能改善接受截肢手术的肌肉骨骼肿瘤患者的临床结局。LigaSure™ 系统是肌肉骨骼肿瘤截肢手术中一种安全有效的止血工具。