Pediatric Mood, Imaging, and NeuroDevelopment (PediMIND) Program, Division of Child Psychiatry, McLean Hospital, Belmont, MA, USA.
Child Psychiatry Hum Dev. 2024 Aug;55(4):1146-1153. doi: 10.1007/s10578-023-01537-6. Epub 2023 Apr 26.
Bipolar disorder (BD) is one of the most impairing psychiatric illnesses. Those with pediatric-onset BD tend to have worse outcomes; therefore, accurate conceptualization is important for aspects of care, such as tailored treatment interventions. Sensation seeking behaviors may be a window into the psychopathology of pediatric-onset BD. Participants with BD and healthy controls (HC) ages 7-27 completed self-report assessments, including the Sensation Seeking Scale- V (SSS-V). Among the BD group, there was a significant positive correlation between the Disinhibition subscale and age. Analyses indicated that the BD group scored lower on the Thrill and Adventure Seeking subscale but higher on the Disinhibition scale when compared to the HC group. We found that individuals with pediatric-onset BD are more likely to engage in socially risky behaviors. These results are an important step in understanding sensation seeking characteristics in BD youth and improving treatment, ultimately helping individuals live a more stable life.
双相情感障碍（BD）是最具致残性的精神疾病之一。那些发病于儿童期的 BD 患者往往预后更差；因此，准确地认识这种疾病对于护理的各个方面都很重要，例如量身定制的治疗干预措施。寻求刺激的行为可能是了解儿童期发病的 BD 患者精神病理学的一个窗口。7-27 岁的 BD 患者和健康对照组（HC）完成了自我报告评估，包括感觉寻求量表-第五版（SSS-V）。在 BD 组中，去抑制分量表与年龄呈显著正相关。分析表明，与 HC 组相比，BD 组在兴奋和冒险寻求分量表上的得分较低，但在去抑制量表上的得分较高。我们发现，患有儿童期发病 BD 的个体更有可能从事社交风险行为。这些结果是理解 BD 青少年感觉寻求特征并改善治疗的重要一步，最终帮助个体过上更稳定的生活。
