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澳大利亚在克罗恩病中应用侧侧等蠕动狭窄成形术的经验。

Australian experience of side-to-side isoperistaltic stricturoplasty in Crohn's disease.

机构信息

Department of Colorectal Surgery, Liverpool Hospital, Liverpool, New South Wales, Australia.

Department of Colorectal Surgery, Concord Hospital, Sydney, New South Wales, Australia.

出版信息

ANZ J Surg. 2023 May;93(5):1287-1293. doi: 10.1111/ans.18440. Epub 2023 Apr 26.

Abstract

BACKGROUND

The Michelassi stricturoplasty has demonstrated efficacy for Crohn's disease in European and American series but has not had uptake in Australia. We report the short-term results of side-to-side isoperistaltic stricturoplasty (SSIS) in an Australian Practice.

METHODS

Between March 2015 and October 2021 SSIS procedures were performed on Crohn's patients with long segment Crohn's strictures associated with obstructive symptoms, despite best medical therapy. Surgical demographics and results were recorded via inpatient and outpatient follow-up in a prospective database.

RESULTS

Twenty-one SSIS performed in 16 patients, nine female, mean age 40 years. Single incision laparoscopic surgery (SILS) was used in 10 patients. The standard Michelassi SSIS used for 11 strictures and a Poggioli variant used for 10. Mean stricture length 32 cm (range 5-100); mean SSIS length 24 cm (range 6-55). Associated bowel resection in seven cases with a mean length of 47 mm. Ten patients had an average of three additional stricturoplasties. Complications included central line sepsis in one, deep surgical site infection in one and superficial wound infection in four patients. Mean duration of operation; 346 min and length of stay 10 days.

CONCLUSION

SSIS techniques are safe for the management of long segment stricturing Crohn's disease. Although not widely used in Australia, surgeons should consider the Michelassi stricturoplasty, and its variants, for long Crohn's strictures as they are isoperistaltic whilst avoiding bowel resection and blind pouches.

摘要

背景

Michelassi 缩窄成形术已在欧美系列中证明对克罗恩病有效,但在澳大利亚尚未得到应用。我们报告了在澳大利亚实践中侧侧等蠕动缩窄成形术(SSIS)的短期结果。

方法

在 2015 年 3 月至 2021 年 10 月期间,对患有与梗阻症状相关的长段克罗恩病狭窄的克罗恩病患者进行了 SSIS 手术,尽管进行了最佳的药物治疗。通过前瞻性数据库中的住院和门诊随访记录手术人口统计学和结果。

结果

16 例患者共进行了 21 次 SSIS,9 例为女性,平均年龄为 40 岁。10 例患者采用单切口腹腔镜手术(SILS)。标准 Michelassi SSIS 用于 11 条狭窄,Poggioli 变体用于 10 条狭窄。平均狭窄长度为 32cm(范围 5-100);SSIS 平均长度为 24cm(范围 6-55)。在 7 例中进行了平均 47mm 的相关肠切除术。10 例患者平均进行了三次额外的缩窄成形术。并发症包括 1 例中心静脉导管感染、1 例深部手术部位感染和 4 例浅表伤口感染。手术平均持续时间为 346 分钟,住院时间为 10 天。

结论

SSIS 技术是治疗长段狭窄性克罗恩病的安全方法。尽管在澳大利亚尚未广泛应用,但对于长段克罗恩病狭窄,外科医生应考虑 Michelassi 缩窄成形术及其变体,因为它们是等蠕动的,同时避免肠切除术和盲袋。

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