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妊娠合并原发性甲状旁腺功能亢进危象的处理。

Management of Hypercalcemic Crisis due to Primary Hyperparathyroidism During Pregnancy.

机构信息

Department of General Surgery, Florida Atlantic University, Boca Raton, FL, USA.

Department of Surgery, Bethesda Hospital East, Boca Raton, FL, USA.

出版信息

Am Surg. 2023 Aug;89(8):3638-3640. doi: 10.1177/00031348231162704. Epub 2023 Apr 27.

Abstract

Primary hyperparathyroidism is the third most common endocrine disorder following diabetes and thyroid disease. Women are affected by primary hyperparathyroidism twice as often as men. The first reported case of hyperparathyroidism during pregnancy was in 1931. More recent data suggests that hyperparathyroidism during pregnancy is diagnosed in .5-1.4% of women. Symptoms of primary hyperparathyroidism, such as fatigue, lethargy, and proximal muscle weakness are nonspecific and could be mistaken as complaints naturally present during pregnancy; however, maternal complications in patients with hyperparathyroidism can be as high as 67%. We present a case of a pregnant patient who presented in hypercalcemic crisis with a concomitant diagnosis of primary hyperparathyroidism.

摘要

原发性甲状旁腺功能亢进是继糖尿病和甲状腺疾病之后的第三大常见内分泌紊乱。女性患原发性甲状旁腺功能亢进的几率是男性的两倍。1931 年首次报道了一例妊娠期间甲状旁腺功能亢进的病例。最近的数据表明,妊娠期间甲状旁腺功能亢进的诊断率为 0.5-1.4%。原发性甲状旁腺功能亢进的症状,如疲劳、嗜睡和近端肌肉无力是非特异性的,可能被误认为是妊娠期间自然出现的症状;然而,甲状旁腺功能亢进患者的母体并发症可高达 67%。我们报告了一例妊娠患者,该患者因并发原发性甲状旁腺功能亢进而出现高钙血症危象。

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