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1
Targeting Small-Conductance Calcium-Activated Potassium Channels in Atrial Fibrillation: Therapeutic Opportunities.
Circ Res. 2023 Apr 28;132(9):1104-1106. doi: 10.1161/CIRCRESAHA.123.322777. Epub 2023 Apr 27.
2
Small-conductance calcium-activated potassium (SK) channels contribute to action potential repolarization in human atria.
Cardiovasc Res. 2014 Jul 1;103(1):156-67. doi: 10.1093/cvr/cvu121. Epub 2014 May 9.
3
Modulation of SK Channels: Insight Into Therapeutics of Atrial Fibrillation.
Heart Lung Circ. 2021 Aug;30(8):1130-1139. doi: 10.1016/j.hlc.2021.01.009. Epub 2021 Feb 26.
6
Atrial fibrillation: Therapeutic potential of atrial K channel blockers.
Pharmacol Ther. 2017 Aug;176:13-21. doi: 10.1016/j.pharmthera.2016.10.003. Epub 2016 Oct 12.
7
Effect of antiarrhythmic drugs on small conductance calcium - activated potassium channels.
Eur J Pharmacol. 2017 May 15;803:118-123. doi: 10.1016/j.ejphar.2017.03.039. Epub 2017 Mar 18.
9
Termination of Vernakalant-Resistant Atrial Fibrillation by Inhibition of Small-Conductance Ca-Activated K Channels in Pigs.
Circ Arrhythm Electrophysiol. 2017 Oct;10(10):e005125. doi: 10.1161/CIRCEP.117.005125.

本文引用的文献

1
Enhanced Ca-Dependent SK-Channel Gating and Membrane Trafficking in Human Atrial Fibrillation.
Circ Res. 2023 Apr 28;132(9):e116-e133. doi: 10.1161/CIRCRESAHA.122.321858. Epub 2023 Mar 17.
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Highly accurate protein structure prediction with AlphaFold.
Nature. 2021 Aug;596(7873):583-589. doi: 10.1038/s41586-021-03819-2. Epub 2021 Jul 15.
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Cardiac small-conductance calcium-activated potassium channels in health and disease.
Pflugers Arch. 2021 Mar;473(3):477-489. doi: 10.1007/s00424-021-02535-0. Epub 2021 Feb 23.
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First Clinical Study with AP30663 - a K 2 Channel Inhibitor in Development for Conversion of Atrial Fibrillation.
Clin Transl Sci. 2020 Nov;13(6):1336-1344. doi: 10.1111/cts.12835. Epub 2020 Jul 29.
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Activation mechanism of a human SK-calmodulin channel complex elucidated by cryo-EM structures.
Science. 2018 May 4;360(6388):508-513. doi: 10.1126/science.aas9466.
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Coupling of SK channels, L-type Ca channels, and ryanodine receptors in cardiomyocytes.
Sci Rep. 2018 Mar 16;8(1):4670. doi: 10.1038/s41598-018-22843-3.
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Small-conductance Ca2+ -activated K+ channels and cardiac arrhythmias.
Heart Rhythm. 2015 Aug;12(8):1845-51. doi: 10.1016/j.hrthm.2015.04.046. Epub 2015 May 5.

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