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右颞顶枕叶皮质致痫区患者报告中存在遗觉记忆的可能性。

The Possibility of Eidetic Memory in a Patient Report of Epileptogenic Zone in Right Temporo-Parietal-Occipital Cortex.

作者信息

Berry Brent M, Miller Laura R, Berns Meaghan, Kucewicz Michal

机构信息

University of Minnesota Medical School, 420 Delaware St SE, Minneapolis, MN 55455, USA.

Neurology Department, University of Minnesota, 516 Delaware St SE, Minneapolis, MN 55455, USA.

出版信息

Life (Basel). 2023 Apr 6;13(4):956. doi: 10.3390/life13040956.

DOI:10.3390/life13040956
PMID:37109485
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10145536/
Abstract

Eidetic memory has been reported in children and in patients with synesthesia but is otherwise thought to be a rare phenomenon. Presented herein is a patient with right-sided language dominance, as proven via multiple functional imaging and neuropsychometric methods, who has a seizure onset zone in the right temporo-parietal-occipital cortex. This patient's medically refractory epilepsy and thus hyperactive cortex could possibly contribute to near eidetic ability with paired-associates learning tasks (in both short-term and long-term retention). There are reports of epilepsy negatively affecting memory, but as far as the authors are aware to date, there is limited evidence of any lesion enhancing cognitive functions (whether through direct lesion or via compensatory mechanism) that would be localized to a seizure onset zone in the dominant temporo-parietal-occipital junction.

摘要

有报道称,儿童和患有联觉的患者具有遗觉记忆,但除此之外,人们认为这是一种罕见现象。本文介绍了一名患者,经多种功能成像和神经心理测量方法证实,其语言优势在右侧,癫痫发作起始区位于右侧颞顶枕叶皮质。该患者药物难治性癫痫以及因此导致的皮质过度活跃,可能有助于其在配对联想学习任务(短期和长期记忆方面)中具备近乎遗觉的能力。有报道称癫痫会对记忆产生负面影响,但就作者目前所知,几乎没有证据表明有任何病变(无论是通过直接病变还是通过代偿机制)会增强认知功能,且病变定位于优势颞顶枕叶交界处的癫痫发作起始区。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00b8/10145536/78b7d31113fb/life-13-00956-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00b8/10145536/3ea9722e88ee/life-13-00956-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00b8/10145536/ec4f9dd78eb5/life-13-00956-sch001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00b8/10145536/3eeafc3cf8df/life-13-00956-sch002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00b8/10145536/d12ed9809b3b/life-13-00956-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00b8/10145536/a7987325a1e8/life-13-00956-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00b8/10145536/78b7d31113fb/life-13-00956-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00b8/10145536/3ea9722e88ee/life-13-00956-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00b8/10145536/ec4f9dd78eb5/life-13-00956-sch001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00b8/10145536/3eeafc3cf8df/life-13-00956-sch002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00b8/10145536/d12ed9809b3b/life-13-00956-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00b8/10145536/a7987325a1e8/life-13-00956-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00b8/10145536/78b7d31113fb/life-13-00956-g004.jpg

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本文引用的文献

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Brain. 2022 Apr 29;145(3):1052-1068. doi: 10.1093/brain/awab345.
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Activities of the Right Temporo-Parieto-Occipital Junction Reflect Spatial Hearing Ability in Cochlear Implant Users.右颞顶枕交界区的活动反映了人工耳蜗使用者的空间听觉能力。
Front Neurosci. 2021 Mar 12;15:613101. doi: 10.3389/fnins.2021.613101. eCollection 2021.
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Dendritic pathology, spine loss and synaptic reorganization in human cortex from epilepsy patients.
人类癫痫患者大脑皮层的树突病理、棘突缺失和突触重组。
Brain. 2021 Feb 12;144(1):251-265. doi: 10.1093/brain/awaa387.
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Unsupervised machine-learning classification of electrophysiologically active electrodes during human cognitive task performance.在人类认知任务执行期间对电生理活性电极进行无监督的机器学习分类。
Sci Rep. 2019 Nov 22;9(1):17390. doi: 10.1038/s41598-019-53925-5.
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Ripple oscillations in the left temporal neocortex are associated with impaired verbal episodic memory encoding.左侧颞叶新皮质中的涟漪振荡与言语情景记忆编码受损有关。
Epilepsy Behav. 2018 Nov;88:33-40. doi: 10.1016/j.yebeh.2018.08.018. Epub 2018 Sep 11.
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Review: Mechanistic target of rapamycin (mTOR) pathway, focal cortical dysplasia and epilepsy.综述:雷帕霉素靶蛋白(mTOR)通路、局灶性皮质发育不良和癫痫。
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The Paired Associates Learning (PAL) Test: 30 Years of CANTAB Translational Neuroscience from Laboratory to Bedside in Dementia Research.配对联想学习(PAL)测试:30年的剑桥神经心理测试自动化成套系统(CANTAB)转化神经科学,从痴呆症研究的实验室到临床应用
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