Machleder H I
West J Med. 1979 Mar;130(3):205-17.
Research into noninvasive techniques for evaluating cerebrovascular insufficiency has shown that hemodynamically significant lesions can be identified with considerable accuracy. Concurrently, recent descriptions of carefully applied medical and surgical therapy indicate that thromboembolic stroke can be effectively prevented when patients are allocated to the proper therapeutic protocols. The approach of these two lines of basic investigation to the clinical focal point of stroke control make it imperative that clinicians review the tools at hand for identifying persons at high risk, as well as the available therapeutic alternatives for effective stroke prevention.
对评估脑血管供血不足的非侵入性技术的研究表明，血流动力学上有显著意义的病变能够以相当高的准确率被识别出来。与此同时，近期对精心应用的药物和手术治疗的描述表明，当患者被分配到适当的治疗方案时，血栓栓塞性中风是可以有效预防的。这两条基础研究路线针对中风控制这一临床焦点的研究方法，使得临床医生必须审视手头用于识别高危人群的工具，以及用于有效预防中风的现有治疗选择。
