《斑秃的当前临床医生报告和患者报告结局测量评估：范围综述》。

An Assessment of Current Clinician-Reported and Patient-Reported Outcome Measures for Alopecia Areata: A Scoping Review.

机构信息

Department of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA; Chobanian & Avedisian School of Medicine, Boston University, Boston, Massachusetts, USA.

Department of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA; Tufts University School of Medicine, Boston, Massachusetts, USA.

出版信息

J Invest Dermatol. 2023 Jul;143(7):1133-1137.e12. doi: 10.1016/j.jid.2023.02.020. Epub 2023 Apr 28.

DOI:10.1016/j.jid.2023.02.020

PMID:37115113

Abstract

Although progress has been made in developing outcome measures for AA, the use of these measures remains unstandardized. A scoping review was conducted to identify the clinician-reported outcome measures (ClinROMs) and patient-reported outcome measures (PROMs) used in assessing and treating AA, the results of which revealed heterogeneity in AA outcome measures. Of 23 research studies ultimately included, only 2 ClinROMs were used by >15% of studies; likewise, of 110 clinical trials evaluated, numerous outcome instruments were used, but only one ClinROM was used by >5% of trials (Severity of Alopecia Tool). These results suggest the need for consensus and standardization in both research and trial settings.

摘要

尽管在开发 AA 的结局测量方面已经取得了进展，但这些测量的使用仍然没有标准化。进行了范围综述，以确定用于评估和治疗 AA 的临床医生报告的结局测量（ClinROM）和患者报告的结局测量（PROM），结果显示 AA 结局测量存在异质性。在最终纳入的 23 项研究中，只有 2 项 ClinROM 被超过 15%的研究使用；同样，在评估的 110 项临床试验中，使用了许多结局工具，但只有一项 ClinROM 被超过 5%的试验使用（脱发严重程度工具）。这些结果表明，无论是在研究还是试验环境中，都需要达成共识并标准化。