Gandor F, Berger L, Gruber D, Warnecke T, Vogel A, Claus I
Neurologisches Fachkrankenhaus für Bewegungsstörungen/Parkinson, Str. nach Fichtenwalde 16, 14547, Beelitz-Heilstätten, Deutschland.
Klinik für Neurologie, Otto-von-Guericke Universität Magdeburg, Magdeburg, Deutschland.
Nervenarzt. 2023 Aug;94(8):685-693. doi: 10.1007/s00115-023-01475-7. Epub 2023 Apr 28.
Dysphagia is a clinically relevant problem in Parkinson's disease as well as in atypical Parkinsonian syndromes, such as multiple system atrophy and diseases from the spectrum of 4‑repeat tauopathies, which affect most patients to a varying degree in the course of their disease. This results in relevant restrictions in daily life due to impaired intake of food, fluids, and medication with a subsequent reduction in quality of life. This article not only gives an overview of the pathophysiological causes of dysphagia in the various Parkinson syndromes, but also presents screening, diagnostic and treatment procedures that have been investigated for the different diseases.
吞咽困难在帕金森病以及非典型帕金森综合征（如多系统萎缩和4R- tau蛋白病谱系疾病）中是一个具有临床相关性的问题，这些疾病在病程中会不同程度地影响大多数患者。由于食物、液体和药物摄入受损，随后生活质量下降，这导致了日常生活中的相关限制。本文不仅概述了各种帕金森综合征中吞咽困难的病理生理原因，还介绍了针对不同疾病所研究的筛查、诊断和治疗程序。
