Fend Falko, Quintanilla-Martinez Leticia, Klapper Wolfram
Institut für Pathologie und Neuropathologie, Eberhard Karls Universität Tübingen, Liebermeisterstr. 8, 72076, Tübingen, Deutschland.
Institut für Pathologie, Sektion Hämatopathologie, Universitätsklinikum Schleswig-Holstein (UKSH), Campus Kiel, Arnold-Heller-Straße 3, Haus U33, 24105, Kiel, Deutschland.
Pathologie (Heidelb). 2023 May;44(3):173-183. doi: 10.1007/s00292-023-01192-7. Epub 2023 Apr 28.
Recently, two new classifications were released: the International Consensus Classification (ICC) drafted by the Clinical Advisory Committee and the short version of the 5th Edition of the WHO classification of hematolymphoid tumors. In light of new clinical, morphological, and molecular data, both classifications also revised the classification of peripheral T‑cell lymphomas. In addition to relatively minor changes in terminology and disease definitions, both new classifications mirror the considerable gain of knowledge on the genetic alterations of different T‑cell lymphoma entities. The present review summarizes the most important changes for T‑cell lymphomas in both classifications, the differences between the classifications, and diagnostically relevant issues.
最近,发布了两种新的分类:由临床咨询委员会起草的国际共识分类(ICC)以及世界卫生组织血液淋巴肿瘤分类第5版的简短版本。鉴于新的临床、形态学和分子数据,这两种分类都对外周T细胞淋巴瘤的分类进行了修订。除了术语和疾病定义方面相对较小的变化外,这两种新分类反映了在不同T细胞淋巴瘤实体的基因改变方面所取得的显著知识进展。本综述总结了这两种分类中T细胞淋巴瘤的最重要变化、分类之间的差异以及诊断相关问题。